Journal ArticleOpen Access
Emblica officinalis improves glycemic status and oxidative stress in STZ induced type 2 diabetic model rats
Author Affiliations
Jashore University of Science and Technology, Islamic University, Jeonbuk National University, Hajee Mohammad Danesh Science and Technology University, ...
Published InAsian Pacific Journal of Tropical Medicine
Year2014
Citations48
Abstract
OBJECTIVE: To evaluate the antidiabetic and antioxidant potential of Emblica officinalis (E. officinalis) fruit on normal and type 2 diabetic rats. METHODS: Type 2 diabetes was induced into the male Long-Evans rats. The rats were divided into nine groups including control groups receiving water, type 2 diabetic controls, type 2 diabetic rats treated with glibenclamide (T2GT) and type 2 diabetic rats treated with aqueous extract of fruit pulp of E. officinalis. They were fed orally for 8 weeks with a single feeding. Blood was collected by cutting the tail tip on 0 and 28 days and by decapitation on 56 day. Packed red blood cells and serum were used for evaluating different biochemical parameters. RESULTS: Four weeks administration of aqueous…
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