Journal ArticleOpen Access
High rates of placental inflammation among samples collected by the Multi-Omics for Mothers and Infants consortium
Authors
Author Affiliations
Reproductive Science Center, Public Health Laboratory Ivo de Carneri, Aga Khan University, Johns Hopkins University, ...
Published InAmerican Journal of Obstetrics and Gynecology
Year2024
Citations4
Abstract
BACKGROUND: The Multi-Omics for Mothers and Infants consortium aims to improve birth outcomes. Preterm birth is a major obstetrical complication globally and causes significant infant and childhood morbidity and mortality. OBJECTIVE: We analyzed placental samples (basal plate, placenta or chorionic villi, and the chorionic plate) collected by the 5 Multi-Omics for Mothers and Infants sites, namely The Alliance for Maternal and Newborn Health Improvement Bangladesh, The Alliance for Maternal and Newborn Health Improvement Pakistan, The Alliance for Maternal and Newborn Health Improvement Tanzania, The Global Alliance to Prevent Prematurity and Stillbirth Bangladesh, and The Global Alliance to Prevent Prematurity and Stillbirth Zambia. The goal was to analyze the morphology and gene expression of samples collected from preterm and uncomplicated term…
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