Hepatoprotective Activity of Methanol Extract of Some Medicinal Plants Against Carbon Tetrachloride Induced Hepatotoxicity in Albino Rats

2 Abstract: The methanol extracts of plant materials of some plants like Casuarina equisetifolia, Cajanus cajan, Glycosmis pentaphylla, Bixa orellana, Argemone mexicana, Physalis minima, Caesalpinia bonduc, belonging to the different family were studied for hepatoprotective activity against Swiss albino rats with liver damage induced by carbon tetrachloride(CCl ). It was found that the methanol extract of B. orellana, C. cajan, 4 G.pentaphylla and C. equisetifolia at a dose of 500 mg/kg body weight exhibited moderate protective effect by lowering the serum levels of alanine aminotransferase(ALT) or Serum Glutamate Pyruvate Transaminase (SGPT), aspartate aminotransferase (AST)or Serum Glutamate Oxaloacetate Transaminase (SGOT) and cholesterol to a significant extent. Other methanol extracts of A. mexicana, P. minima and C. bonduc had no effect of…