Critical pathway analysis to determine key uncertainties in net impacts on disease burden in Bangladesh of arsenic mitigation involving the substitution of arsenic bearing for groundwater drinking water supplies

It has been increasingly recognised that calculation of the disease burden due to populations, such as in Bangladesh, extensively using hazardous arsenic bearing well waters, must explicitly account for the trade-off between diarrhoeal disease incidence and that of arsenic-related diseases. This is because it is likely that moves to alternative drinking water sources, be they surface waters or even more distant groundwaters, without further mitigation would result in a concurrent increase in diarrhoeal disease. In this paper, we update the model of Lokuge[ 1 Lokuge, K. M., Smith, W., Caldwell, B., Dear, K. and Milton, A. H. 2004. The effect of arsenic mitigation interventions on disease burden in Bangladesh. Environ. Health Perspect., 112: 1172–1177. [Crossref], [PubMed], [Web of Science ®]…