Journal ArticleOpen Access
Antidiabetic Effects of the Different Fractions of Ethanolic Extracts of <i>Ocimum sanctum</i> in Normal and Alloxan Induced Diabetic Rats
Authors
Author Affiliations
International Islamic University Chittagong, Atish Dipankar University of Science and Technology, University of Rajshahi
Published InJournal of Scientific Research
Year2009
Citations45
Abstract
The antidiabetic effects of Ethyl acetate (Et-Ac), Petroleum-ether (Pet-ether), and Chloroform fractions from ethanolic extract of the leaves of Ocimum sanctum were investigated in normal and alloxan induced diabetic rats (AIDRs). The effect of these fractions (200 mg/kg body weight i.p) on fasting blood glucose (FBG), total cholesterol (TC), triglyceride (TG), serum glutamate oxaloacetate transaminases, serum glutamate pyruvate transaminases (SGOT, SGPT) level, and liver glycogen content were investigated in AIDRs and found significant effects. The most significant reduction of FBG level of around 80.19% was observed for Et-Ac fraction in AIDRs. A significant reduction (p< 0.01) in serum TC and TG level of 54.49% and 79.78% respectively was also found for Et-Ac fraction of O. sanctum. The hypoglycemic and hypolipidemic…
View at Publisher
BORR does not host full-text PDFs. The button above takes you to the original publisher.