Diagnostic Performance of Multimodal Sound Touch Elastography for Differentiating Benign and Malignant Breast Masses

Objectives Evaluating the value of screening breast masses by separate or combined use of multimodal Sound Touch Elastography. Methods Women with 159 masses (mean size, 14.86 ± 6.57 mm; range, 5.30–30.00 mm) were enrolled in the study. The pathology results were adopted as diagnostic standards. The abilities of Young's modulus (E), shear modulus (G), and shear wave (C) to differentiate malignant and benign breast masses based on receiver operating characteristic curves were evaluated, and the optimal cutoff values were obtained. Sensitivity, specificity, positive likelihood ratio, and negative likelihood ratio were calculated. Then, the values were combined to perform an overall analysis of Sound Touch Elastography using evidence‐based medicine, construct forest plots, and calculate areas under the summary receiver operating characteristic…