Unveiling the emerging concern of per- and polyfluoroalkyl substances (PFAS) and their potential impacts on estuarine ecosystems

Per- and polyfluoroalkyl substances (PFAS) have become ubiquitous chemicals that pose potentially serious threats to both human health and the integrity of the ecosystem. This review compiles current knowledge on PFAS contamination in estuaries, focusing on sources, abundance, distribution, fate, and toxic mechanisms. It also addresses the health risks associated with these compounds and identifies research gaps, offering recommendations for future studies. Estuaries are essential for maintaining biodiversity and serve as protective natural buffers against pollution flowing from land to sea. However, PFAS, known for their persistence and bioaccumulation potential, are detected in estuarine waters, sediments, and biota worldwide, with varying concentrations based on geographic locations and environmental matrices. Sources of PFAS in estuaries include routine items like nonstick kitchenware,…