Endometrial changes in Infertile Women with Polycystic Ovary Syndrome after taking Letrozole in Comparison to Clomiphene Citrate

Background: The endometrium is a receptor organ for most of the hormones involved in fertility and therefore the study of its morphology is thought to explain the mysteries of implantation failure. Many studies showed that Clomiphene Citrate impairs endometrial development due to antiestrogenic effects and long half-life. Conversely Letrozole shows a positive effect on follicle and endometrium. Objective: To assess the endometrium in infertile Polycystic Ovary Syndrome women by Transvaginal Sonography after giving ovulation induction by Clomiphene Citrate versus Letrozole. Materials and Methods: This Comparative cross-sectional study was conducted on sixty diagnosed Polycystic Ovary Syndrome infertile women in the Reproductive Endocrinology & Infertility Unit of Dhaka medical College Hospital, Dhaka, from January 2021 to December 2021. The patients who took…