Spirulina platensis supplementation remediates microplastics-induced growth inhibition and stress in Nile tilapia, Oreochromis niloticus

• Growth, blood profiles and intestinal histomorphology of Nile tilapia were significantly affected upon exposure to microplastics • Upregulation of oxidative stress-related (SOD & CAT) and immune-related (TNF-α, IFN-γ, and IL-1β) genes expression • Suplimentation with Spirulina in feed significantly restored the growth hindrance and stress in fish • Spirulina showed ameliorative effects on damage repaired induced by microplastics Microplastics (MP) are ubiquitous pollutants and their ingestion exerts deleterious effects on fish physiology. An effort was made in the present study to counteract the negative impacts of MP by supplementation of Spirulina platensis (Spir.) in feed. A 42-day long experiment investigated the efficacy of Spir. in attenuating polyamide microplastics (PA-MP) instigated blood toxicity, growth retardation and stress in Nile tilapia…