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Peer Review #2 of "Adaptation of metal and antibiotic resistant traits in novel β-Proteobacterium Achromobacter xylosoxidans BHW-15 (v0.1)"
Authors
Author Affiliations
University of Dhaka, Noakhali Science and Technology University
Year2019
Abstract
Chromosomal co-existence of metal and antibiotic resistance genes in bacteria offers a new perspective to the bacterial resistance proliferation in contaminated environment.In this study, an arsenotrophic bacterium Achromobacter xylosoxidans BHW-15, isolated from Arsenic (As) contaminated tubewell water in Bogra district of Bangladesh, was analyzed using high throughput Ion Torrent PGM complete genome sequencing scheme to reveal its adaptive potentiality.The assembled draft genome of A. xylosoxidans BHW-15 was 6.3 Mbp containing 5782 functional genes, 1845 pseudo genes, and 3 incomplete phage signature regions.Comparative genome study suggested the bacterium to be a novel strain of A. xylosoxidans showing significant dissimilarity with other relevant strains in metal resistance gene islands.Thirty five metal resistance genes along with arseniteoxidizing aioSXBA, arsenate reducing arsRCDAB, and mercury…
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