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Journal ArticleOpen Access

Generative data-engine foundation model for universal few-shot 2D vascular image segmentation

Author Affiliations
Southeast University, Harbin Institute of Technology, Ningbo Institute of Industrial Technology, Beijing Institute of Technology, ...
Published InMedical Image Analysis
Year2026

Abstract

The segmentation of 2D vascular structures via deep learning holds significant clinical value but is hindered by the scarcity of annotated data, severely limiting its widespread application. Developing a universal few-shot vascular segmentation model is highly desirable, yet remains challenging due to the need for extensive training and the inherent complexities of vascular imaging. In this work, we propose UniVG (Generative Data-engine Foundation Model for Universal Few-shot 2D Vascular Image Segmentation), a novel approach that learns the compositionality of vascular images and constructing a generative foundation model for robust vascular segmentation. UniVG enables the synthesis and learning of diverse and realistic vascular images through two key innovations: 1) Compositional learning for flexible and diverse vascular synthesis: It decomposes and recombines…
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