Effects of Sex, Age and Comorbidities on the Risk of Infection and Death Associated with COVID-19: A Meta-Analysis of 47807 Confirmed Cases

Background: Evidence for the associations of sex, age and comorbidities on the risk of death and infection caused by 2019-nCoV is not well-established. It was aimed to build a robust evidence by estimating aggregated risk for sex, age and comorbidities on the death and infection cases of COVID-2019. Methods: Literatures were searched in PubMed and other resources from the inception to March 25, 2020 using keywords as "2019 novel coronavirus" or "2019-nCoV" or "SARS-CoV-2" or "COVID-19" AND "clinical outcomes or death or clinical features". Pooled relative risk (RR) was calculated by random effect model using RevMan software where statistical significance was set as <0.05 (2-sided). Findings: In total, 21 studies comprising of 47,807 confirmed cases of COVID-19 were included. Male…