Journal ArticleOpen Access
Antiproliferative and antioxidant potentials of bioactive edible vegetable fraction of <i>Achyranthes ferruginea</i> Roxb. in cancer cell line
Authors
Author Affiliations
International Islamic University Chittagong, University of Tsukuba, University of Rajshahi, Varendra University, ...
Published InFood Science & Nutrition
Year2021
Citations67
Abstract
Abstract In the present study, the aerial parts of Achyranthes ferruginea underwent investigation of their in vitro antioxidant and free radical‐scavenging activities in cell‐free conditions, their phytoconstituents using gas chromatography‐mass spectrometry (GC‐MS), and their cytotoxic activity in HeLa cells. A. ferruginea was extracted with 80% methanol and successively fractionated with solvents to yield petroleum ether (PEF), chloroform (CHF), ethyl acetate (EAF), and aqueous (AQF) fractions. GC‐MS analysis revealed that CHF contained ten phytoconstituents, including different forms of octadecanoic acid methyl esters. The total antioxidant and ferric‐reducing antioxidant capacities of the extracts and the standard catechin (CA) were as follows: CA >CHF >PEF >CME (crude methanolic extract) >EAF >AQF, and CA >CHF >EAF >PEF >AQF >CME, respectively. CHF showed the highest…
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