Influence of NaCl and temperature on the interaction between cephradine monohydrate and surfactants: Conductivity and UV–visible measurements

The formulation of drug considering the body fluid ingredients is important and therefore study of the interaction of drug-surfactant in fluid ingredients medium is very significant. Herein, we applied a conductivity technique to insight the interaction of cephradine monohydrate (CDM) drug with cationic surfactant- cetyltrimethylammonium bromide (CTAB) and anionic surfactant- sodium dodecyl sulfate (SDS)) while UV–visible spectroscopic was employed to observe the interaction of CDM with non-ionic surfactant, triton X-100 (TX-100). The experimental temperature ranges were 303.15–328.15 K and 293.15–323.15 K for CDM + CTAB and CDM + SDS systems respectively in the case of the conductivity study whereas for UV–visible spectroscopic study the temperature was kept in the range of 298.15–318.15 K. The values of critical micelle concentration (CMC)…