ReviewUnknown
How the association between obesity and inflammation may lead to insulin resistance and cancer
Author Affiliations
Noakhali Science and Technology University, Atish Dipankar University of Science and Technology, Mawlana Bhashani Science and Technology University, State University of Bangladesh, ...
Published InDiabetes & Metabolic Syndrome Clinical Research & Reviews
Year2019
Citations147
Abstract
BACKGROUND AND OBJECTIVES Obesity is associated with metabolic dysfunction and over nutrition. Increased body mass index and obesity are strongly amalgamated with changes in the physiological function of adipose tissue, leading to altered secretion of adipocytokines, inflammatory mediators release as well as chronic inflammation and insulin resistance. The purposes of this study were to review the evidence of how obesity and inflammation may lead to insulin resistance and cancer. SUMMARY Recent findings suggested that increased level of inflammatory mediators in obesity, plays an introductory and cabalistic role in the development of different types of inflammatory disorders including type 2 diabetes mellitus. Link between elevated body mass index and type 2 diabetes mellitus (T2DM). Several of the factors-such as increased levels…
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