Journal ArticleOpen Access
Trends in incidence, prevalence, and survival of breast cancer in the United Kingdom from 2000 to 2021
Author Affiliations
Nuffield Orthopaedic Centre, University of Oxford, Institut Universitari d'Investigació en Atenció Primària Jordi Gol, Northeastern University, ...
Published InScientific Reports
Year2024
Citations25
Abstract
Breast cancer is the most frequently diagnosed cancer in females globally. However, we know relatively little about trends in males. This study describes United Kingdom (UK) secular trends in breast cancer from 2000 to 2021 for both sexes. We describe a population-based cohort study using UK primary care Clinical Practice Research Datalink (CPRD) GOLD and Aurum databases. There were 5,848,436 eligible females and 5,539,681 males aged 18+ years, with ≥ one year of prior data availability in the study period. We estimated crude breast cancer incidence rates (IR), prevalence and survival probability at one-, five- and 10-years after diagnosis using the Kaplan-Meier method. Analyses were further stratified by age. Crude IR of breast cancer from 2000 to 2021 was 194.4…
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