Journal ArticleOpen Access
Involvement of Tsukushi in diverse developmental processes
Author Affiliations
Kumamoto University, Mawlana Bhashani Science and Technology University
Published InJournal of Cell Communication and Signaling
Year2018
Citations28
Abstract
Tsukushi (TSK) is a small signaling molecule which takes part in different developmental processes of multiple vertebrate organisms. The diverse activity of TSK depends on its ability to bind various intermediate molecules from different major signaling pathways. Interactions of TSK with BMP, FGF, TGF-β and Wnt pathways have already been confirmed. In this review, we will introduce the latest information regarding the involvement of TSK in developmental events. We suggest a fine tuning role for TSK in multiple signaling cascades. Also, we recommend further studies on the developmental role of TSK to fully reveal its potential.
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