ReviewOpen Access
Prenatal Environmental Metal Exposure and Preterm Birth: A Scoping Review
Authors
Author Affiliations
Johns Hopkins University, Georgetown University, Biomedical Research Foundation, International Centre for Diarrhoeal Disease Research
Published InInternational Journal of Environmental Research and Public Health
Year2021
Citations75
Abstract
Preterm birth (PTB) and its complications are the leading causes of under-five year old child deaths, accounting worldwide for an estimated one million deaths annually. The etiology of PTB is complex and multifactorial. Exposures to environmental metals or metalloids are pervasive and prenatal exposures to them are considered important in the etiology of PTB. We conducted a scoping review to determine the extent of prenatal exposures to four metals/metalloids (lead, mercury, cadmium and arsenic) and their association with PTB. We reviewed original research studies published in PubMed, Embase, the Cochrane Library, Scopus, POPLINE and the WHO regional indexes from 2000 to 2019; 36 articles were retained for full text review. We documented a higher incidence of PTB with lead and…
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