Conductivity and cloud point studies of the interaction of lomefloxacin hydrochloride with anionic and nonionic surfactants in electrolytes solution

The interaction of lomefloxacin hydrochloride (LMFH) drug (utilized to treat different bacterial infections) with anionic (sodium dodecyl sulfate (SDS)) and nonionic (triton X-100 (TX-100)) surfactants in electrolytes media has been carried out applying the conductometric and cloud point (CP) measurement methods. SDS is very useful to prohibit different viral infections and to extract DNA/RNA. Two critical micelle concentrations (cmc) were observed for LMFH + SDS mixtures within the investigated surfactant concentration. The cmc values of SDS increase monotonically with the increase of the LMFH concentration. The cmc values of LMFH + SDS mixtures were reduced as the ionic strength of electrolytes increases. In the case of the LMFH + SDS mixture, the cmc values showed reverse U-shaped change with the…