Journal ArticleOpen Access
Long COVID‐19: Objectifying most self‐reported neurological symptoms
Author Affiliations
Forschungszentrum Jülich, Jülich Aachen Research Alliance, RWTH Aachen University, Universitätsklinikum Aachen, ...
Published InAnnals of Clinical and Translational Neurology
Year2022
Citations132
Abstract
Abstract Objectives We aimed to objectify and compare persisting self‐reported symptoms in initially hospitalized and non‐hospitalized patients after infection with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) by applying clinical standardized measures. Methods We conducted a cross‐sectional study of adult patients with confirmed SARS‐CoV‐2 infection including medical history, neurological examination, blood markers, neuropsychological testing, patient‐reported outcome measures (PROMs), and brain magnetic resonance imaging (MRI). Results Fifty patients with persisting symptoms for at least 4 weeks were included and classified by initial hospitalization status. Median time from SARS‐CoV‐2 detection to investigation was 29.3 weeks (range 3.3–57.9). Although individual cognitive performance was generally within the normative range in both groups, mostly mild deficits were found in attention, executive functions, and memory. Hospitalized…
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