Mohammed Eslam, Shiv Kumar Sarin, Vincent Wai‐Sun Wong, Jian-Gao Fan et al.
Metabolic associated fatty liver disease (MAFLD) is the principal worldwide cause of liver disease and affects nearly a quarter of the global population. The objective of this work was to present the clinical practice guidelines of the Asian Pacific Association for the Study of the Liver (APASL) on ...
William C. Hsu, Maria Rosario G. Araneta, Alka M. Kanaya, Jane L. Chiang et al.
According to the U.S. Census Bureau, an Asian is a person with origins from the Far East (China, Japan, Korea, and Mongolia), Southeast Asia (Cambodia, Malaysia, the Philippine Islands, Thailand, Vietnam, Indonesia, Singapore, Laos, etc.), or the Indian subcontinent (India, Pakistan, Bangladesh, Bhu...
Xiaodong Zhou, Giovanni Targher, Christopher D. Byrne, Virend K. Somers et al.
Background Fatty liver disease in the absence of excessive alcohol consumption is an increasingly common condition with a global prevalence of ~ 25–30% and is also associated with cardiovascular disease (CVD). Since systemic metabolic dysfunction underlies its pathogenesis, the term metabolic (dysfu...
Nurshad Ali, Rakib Miah, Mahmudul Hasan, Zitu Barman et al.
Elevated levels of serum uric acid (SUA) have been suggested to associate with cardiovascular disease, diabetes and metabolic syndrome (MetS). However, information is limited on the association between SUA and MetS in general adults. This study aimed to assess the relationship of SUA with MetS and i...
Stephanie Bell, Brenda Stade, James N. Reynolds, Carmen Rasmussen et al.
BACKGROUND: Fetal alcohol spectrum disorder (FASD) is the umbrella term that describes the range of adverse developmental outcomes that may occur in the offspring of mothers who drink alcohol during pregnancy. FASD is associated with several comorbidities including epilepsy. The objective of the stu...
Md Jamal Uddin, Ee Hyun Kim, Md. Abdul Hannan, Hunjoo Ha
The global burden of chronic kidney disease (CKD) intertwined with cardiovascular disease has become a major health problem. Oxidative stress (OS) plays an important role in the pathophysiology of CKD. The nuclear factor erythroid 2-related factor 2 (Nrf2)-antioxidant responsive element (ARE) antiox...
Oriol Morales‐Ibanez, Marlene Domínguez, Sung Hwan Ki, Miguel Marcos et al.
UNLABELLED: We identified, in the transcriptome analysis of patients with alcoholic hepatitis (AH), osteopontin (OPN) as one of the most up-regulated genes. Here, we used a translational approach to investigate its pathogenic role. OPN hepatic gene expression was quantified in patients with AH and o...
Nurshad Ali, Shakil Mahmood, Farjana Islam, Shahnaz Rahman et al.
Experimental evidence suggests a causal role of serum uric acid (SUA) in hypertension development. Currently, there are few data available on the association between SUA and hypertension; data from Bangladeshi adults are not available yet. This study evaluated the association of SUA with hypertensio...
Divya Jain, Priya Chaudhary, Nidhi Varshney, Khandaker Sabit Bin Razzak et al.
Smoking a cigarette generates over 4000 chemicals that have a deleterious impact on each part of the human body. It produces three main severe effects on the liver organ: oncogenic, immunological, and indirect or direct toxic effects. It results in the production of cytotoxic substances, which raise...
Sadaqur Rahman, Shiful Islam, Md Tangigul Haque, Rahanuma Raihanu Kathak et al.
BACKGROUND: Hypertension is a major contributing factor to cardiovascular disease and is a leading cause of death in the world. The association between hepatic enzymes and hypertension has been reported in limited studies and the findings are inconsistent; data from Bangladeshi adults are not availa...
Shahinul Alam, Shah Mohammad Fahim, Muhammad Abdul Baker Chowdhury, Md Zakiul Hassan et al.
Background and Aim Non‐alcoholic fatty liver disease (NAFLD) is a significant cause of hepatic dysfunction and liver‐related mortality. As there is a lack of population‐based prevalence data in a representative sample of general population, we aimed to estimate the prevalence and risk factors of NAF...
Augusto Di Castelnuovo, Simona Costanzo, Marialaura Bonaccio, Patrick McElduff et al.
AIM: To test the association of alcohol consumption with total and cause-specific mortality risk. DESIGN: Prospective observational multi-centre population-based study. SETTING: Sixteen cohorts (15 from Europe) in the MOnica Risk, Genetics, Archiving and Monograph (MORGAM) Project. PARTICIPANTS: A t...
Israt Ara Hossain, Md Mijanur Rahman Shah, Mohammad Khalilur Rahman, Liaquat Ali
Aims Nonalcoholic fatty liver disease (NAFLD) is a major cause of liver-related morbidity and is frequently associated with insulin resistance (HOMA-IR) syndrome. Recently serum gamma glutamyl transferase (GGT) has been considered as surrogate marker of NAFLD leading to oxidative stress and hepatoce...
Md Shariful Islam, KM Saif‐Ur‐Rahman, Md Mofijul Islam Bulbul, Deepak Singh
BACKGROUND: Tobacco consumption causes almost 638,000 premature deaths per year in India. This study sought to examine the prevalence and determinants of tobacco use among men in India. METHODS: We analyzed data from the fourth round of the National Family Health Survey in India. These nationally re...
Noyan Hossain Molla, Rahanuma Raihanu Kathak, Abu Hasan Sumon, Zitu Barman et al.
Serum uric acid (SUA) level has been suggested to be associated with cardiovascular disease, diabetes and metabolic syndrome. However, little is known about the relationship between SUA and liver enzymes activity in the general population. The present study aimed to assess the relationship between S...