Iftekhar Ahmed, Md. Bodiuzzaman Rabbi, Sakina Sultana
BACKGROUND: Antibiotic resistance (ABR) is a worldwide problem and Bangladesh is a major contributor to this owing to its poor healthcare standards, along with the misuse and overuse of antibiotics. This systematic review was conducted to summarize the present scenario of ABR in Bangladesh, to ident...
Emily K. Rousham, Leanne Unicomb, Mohammad Aminul Islam
Antibiotic resistance (ABR) is recognized as a One Health challenge because of the rapid emergence and dissemination of resistant bacteria and genes among humans, animals and the environment on a global scale. However, there is a paucity of research assessing ABR contemporaneously in humans, animals...
Patrick Munk, Christian Brinch, Frederik Duus Møller, Thomas Nordahl Petersen et al.
Antimicrobial resistance (AMR) is a major threat to global health. Understanding the emergence, evolution, and transmission of individual antibiotic resistance genes (ARGs) is essential to develop sustainable strategies combatting this threat. Here, we use metagenomic sequencing to analyse ARGs in 7...
Sandra Chibani-Chennoufi, J Sidoti, Anne Bruttin, Elizabeth Kutter et al.
Four T4-like coliphages with broad host ranges for diarrhea-associated Escherichia coli serotypes were isolated from stool specimens from pediatric diarrhea patients and from environmental water samples. All four phages showed a highly efficient gastrointestinal passage in adult mice when added to d...
Tran Thuy Chau, James Campbell, Claudia M. Galindo, Nguyễn Văn Minh Hoàng et al.
ABSTRACT This study describes the pattern and extent of drug resistance in 1,774 strains of Salmonella enterica serovar Typhi isolated across Asia between 1993 and 2005 and characterizes the molecular mechanisms underlying the reduced susceptibilities to fluoroquinolones of these strains. For 1,393 ...
Andrew J. Stewardson, Kalisvar Marimuthu, Sharmila Sengupta, Arthur Allignol et al.
BACKGROUND Low-income and middle-income countries (LMICs) are under-represented in reports on the burden of antimicrobial resistance. We aimed to quantify the clinical effect of carbapenem resistance on mortality and length of hospital stay among inpatients in LMICs with a bloodstream infection due ...
Golam Rabbani, Thomas Butler, Joseph A. Knight, S. C. Sanyal et al.
To evaluate the antisecretory activity of berberine sulfate (BS), we studied 165 adult patients with acute diarrhea due to enterotoxigenic Escherichia coli (ETEC) and Vibrio cholerae in randomized controlled trials. In patients with ETEC diarrhea who received 400 mg of BS in a single oral dose, the ...
Firdausi Qadri, Swadesh K. Das, Abu Syed Golam Faruque, George J. Fuchs et al.
The prevalence of toxin types and colonization factors (CFs) of enterotoxigenic Escherichia coli (ETEC) was prospectively studied with fresh samples (n = 4,662) obtained from a 2% routine surveillance of diarrheal stool samples over 2 years, from September 1996 to August 1998. Stool samples were tes...
Shah M. Faruque, John J. Mekalanos
The identification of accessory genetic elements (plasmids, phages and chromosomal 'pathogenicity islands') encoding virulence-associated genes has facilitated our efforts to understand the origination of pathogenic microorganisms. Toxigenic Vibrio cholerae, the etiologic agent of cholera, represent...
Yunus Ahmed, Ji Lu, Zhiguo Yuan, Philip L. Bond et al.
Antibiotic resistance has been recognized as a major threat to public health worldwide. Inactivation of antibiotic resistant bacteria (ARB) and degradation of antibiotic resistance genes (ARGs) are critical to prevent the spread of antibiotic resistance in the environment. Conventional disinfection ...
Prabhat K. Talukdar, Md Mizanur Rahman, Mahdia Rahman, Ashikun Nabi et al.
BACKGROUND: Unsafe water supplies continue to raise public health concerns, especially in urban areas in low resource countries. To understand the extent of public health risk attributed to supply water in Dhaka city, Bangladesh, Escherichia coli isolated from tap water samples collected from differ...
R. Bradley Sack, Mahbubur Rahman, Mohammad Yunus, Eradul H. Khan
Antimicrobial resistance is becoming increasingly important in the treatment of enteric infections, particularly those due to Shigella, Vibrio cholerae, enterotoxigenic Escherichia coli (associated with traveler's diarrhea), and Salmonella typhi. The rate of antimicrobial resistance is highest in th...
Roksana Hoque, Syed Masud Ahmed, Nahitun Naher, Mohammad Aminul Islam et al.
BACKGROUND: Antimicrobial resistance (AMR) has become an emerging issue in the developing countries as well as in Bangladesh. AMR is aggravated by irrational use of antimicrobials in a largely unregulated pluralistic health system. This review presents a 'snap shot' of the current situation includin...
Debasish Saha, Mohammad Mahbubul Karim, Wasif Ali Khan, Sabeena Ahmed et al.
BACKGROUND: Single-dose azithromycin is effective in the treatment of severe cholera in children, but its effectiveness in adults has not been evaluated. METHODS: We conducted a double-blind, randomized trial comparing the equivalence of azithromycin and ciprofloxacin (each given in a single 1-g dos...
Joseph A. Lewnard, Esmita Charani, Alec Gleason, Li Yang Hsu et al.
National action plans enumerate many interventions as potential strategies to reduce the burden of bacterial antimicrobial resistance (AMR). However, knowledge of the benefits achievable by specific approaches is needed to inform policy making, especially in low-income and middle-income countries (L...