Allison M. Pritchett, Douglas W. Mahoney, Steven J. Jacobsen, Richard J. Rodeheffer et al.
Objectives We examined the association between diastolic function and left atrial volume indexed to body surface area (LAVi) in a population-based study. Background Atrial enlargement has been suggested as a marker of the severity and duration of diastolic dysfunction (DD). However, the association ...
David H. Birnie, Jeff S. Healey, George A. Wells, Atul Verma et al.
BACKGROUND: Many patients requiring pacemaker or implantable cardioverter-defibrillator (ICD) surgery are taking warfarin. For patients at high risk for thromboembolic events, guidelines recommend bridging therapy with heparin; however, case series suggest that it may be safe to perform surgery with...
Oliver Guttmann, Mohammad Shafiqur Rahman, Constantinos O’Mahony, Aris Anastasakis et al.
CONTEXT: HCM is commonly associated with AF. Current guidelines for AF management omit detailed advice for HCM because of a lack of clinical prediction tools that estimate the risk of developing AF and an absence of adequately powered treatment studies. OBJECTIVE: To critically review current litera...
Jeetendra Patel, Daniel D. Borgeson, Marion E. Barnes, Charanjit S. Rihal et al.
Background Mitral regurgitation (MR) may develop in patients with advanced systolic congestive heart failure (CHF) without organic mitral valve disease and contribute to worsening symptoms and survival. Surgical mitral annuloplasty improves symptoms in patients with advanced CHF, and percutaneous ap...
Charles R. Kerr, Stuart J. Connolly, Hoshiar Abdollah, Robin S. Roberts et al.
BACKGROUND: The Canadian Trial of Physiological Pacing (CTOPP) reported that the risk of stroke or cardiovascular death was similar between patients receiving ventricular versus physiological pacemakers at the end of the original follow-up period of 3 years. However, the occurrence of atrial fibrill...
Linda P.T. Joosten, Sander van Doorn, Peter M. van de Ven, B T G Kohlen et al.
BACKGROUND: There is ambiguity whether frail patients with atrial fibrillation managed with vitamin K antagonists (VKAs) should be switched to a non-vitamin K oral anticoagulant (NOAC). METHODS: or with valvular atrial fibrillation were excluded. Follow-up was 12 months. The cause-specific hazard ra...
Yu Horiuchi, Shuzou Tanimoto, A. H. M. Mahbub Latif, Kevin Y. Urayama et al.
BACKGROUND Acute heart failure (AHF) is a heterogeneous disease caused by various cardiovascular (CV) pathophysiology and multiple non-CV comorbidities. We aimed to identify clinically important subgroups to improve our understanding of the pathophysiology of AHF and inform clinical decision-making....
Luke Ogonda, Janet Hill, E. Doran, J Dennison et al.
AIMS: The aim of this study was to present data on 11 459 patients who underwent total hip (THA), total knee (TKA) or unicompartmental knee arthroplasty (UKA) between November 2002 and April 2014 with aspirin as the primary agent for pharmacological thromboprophylaxis. PATIENTS AND METHODS: We analy...
Gary E. Raskob, Harry R. Büller, Martin H. Prins, Annelise Segers et al.
Background New oral anticoagulants may simplify long-term therapy by eliminating the need for laboratory monitoring. Edoxaban is an oral, direct inhibitor of factor Xa that is given in a fixed dose once daily. Objective and methods The Hokusai-VTE study is a randomized, double-blind trial to evaluat...
Philip Joseph, Jeff S. Healey, Parminder Raina, Stuart J. Connolly et al.
AIMS: To compare the prevalence of electrocardiogram (ECG)-documented atrial fibrillation (or flutter) (AF) across eight regions of the world, and to examine antithrombotic use and clinical outcomes. METHODS AND RESULTS: Baseline ECGs were collected in 153 152 middle-aged participants (ages 35-70 ye...
Shirin Jalini, Rajasumi Rajalingam, Rosane Nisenbaum, Angelo Dave Javier et al.
<h3>Objective</h3> To investigate the prevalence and clinical determinants of atrial cardiopathy in patients with embolic stroke of unknown source (ESUS) and compare with other established stroke etiologies. <h3>Methods</h3> In a cross-sectional study of 846 consecutive patients with ischemic stroke...
Xiangyu Zhang, Jianqing Li, Zhipeng Cai, Li Zhang et al.
Nowadays, deep learning-based models have been widely developed for atrial fibrillation (AF) detection in electrocardiogram (ECG) signals. However, owing to the inevitable over-fitting problem, classification accuracy of the developed models severely differed when applying on the independent test da...
Tatjana Potpara, Gheorghe‐Andrei Dan, Elina Trendafilova, Artan Goda et al.
Data on the management of atrial fibrillation (AF) in the Balkan Region are limited. The Serbian AF Association (SAFA) prospectively investigated contemporary 'real-world' AF management in clinical practice in Albania, Bosnia&Herzegovina, Bulgaria, Croatia, Montenegro, Romania and Serbia through a 1...
K Salathia, J M Barber, E. L. MCILMOYLEI, J. NICHOLAS et al.
A double blind randomized study of 800 patients was carried out to determine if very early intervention with metoprolol (15 mg I.V. followed by oral administration) in suspected acute myocardial infarction affected overall mortality in selected subgroups, (age, site of infarct, delay to intervention...
M Nair, Linda K. George, Santhosh Koshy
This article reviews the safety and efficacy of ibutilide for use in patients with atrial fibrillation and flutter. Ibutilide, a class III antiarrhythmic agent, is primarily used for conversion of atrial flutter and fibrillation and is a good alternative to electrical cardioversion. Ibutilide has a ...