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16+ results
Field: Autism Spectrum Disorder Research

Genetic Variation in the 6p22.3 Gene DTNBP1, the Human Ortholog of the Mouse Dysbindin Gene, Is Associated with Schizophrenia

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Richard E. Straub, Yuxin Jiang, Charles J. MacLean, Yunlong Ma et al.

Journal: The American Journal of Human Genetics
Year: 2002
Citations: 837

Prior evidence has supported the existence of multiple susceptibility genes for schizophrenia. Multipoint linkage analysis of the 270 Irish high-density pedigrees that we have studied, as well as results from several other samples, suggest that at least one such gene is located in region 6p24-21. In...

Life SciencesBiochemistry, Genetics and Molecular BiologyGeneticsOpen Access
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Prevalence of comorbid psychiatric disorders among people with autism spectrum disorder: An umbrella review of systematic reviews and meta-analyses

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Md Mahbub Hossain, Nusrat Khan, Abida Sultana, Ping Ma et al.

Journal: Psychiatry ResearchYear: 2020Citations: 478

With ever-increasing prevalence of various mental disorders worldwide, a comprehensive evaluation of the prevalence of co-occurring psychiatric disorders among individuals with autism spectrum disorder (ASD) is needed to strengthen the knowledge base. This umbrella review aims to summarize the curre...

Life SciencesNeuroscienceCognitive Neuroscience
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Apathy in Parkinson's disease: A systematic review and meta‐analysis

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Melina G.H.E. den Brok, Jan Willem van Dalen, Willem A. van Gool, Eric P. Moll van Charante et al.

Journal: Movement DisordersYear: 2015Citations: 373

Apathy is a frequently reported neuropsychiatric symptom in Parkinson's disease (PD), but its prevalence and clinical correlates are debated. We aimed to address these issues by conducting a systematic review and meta-analysis. Embase, Medline/PubMed, and PsychINFO databases were searched for releva...

Health SciencesMedicineNeurologyOpen Access
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FUNCTIONAL CLASSES AND EQUIVALENCE RELATIONS

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Murray Sidman, Constance K. Wynne, Russell W. Maguire, Thomas R. E. Barnes

Journal: Journal of the Experimental Analysis of BehaviorYear: 1989Citations: 242

Three adult subjects were taught a set of two-choice simultaneous discriminations, with three positive and three negative stimuli; all possible combinations of positive and negative stimuli yielded nine different pairs. The discriminations were repeatedly reversed and rereversed, the former positive...

Social SciencesPsychologyDevelopmental and Educational PsychologyOpen Access
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Machine Learning-Based Models for Early Stage Detection of Autism Spectrum Disorders

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Tania Akter, Md. Shahriare Satu, Md. Imran Khan, Mohammad Hanif Ali et al.

Journal: IEEE AccessYear: 2019Citations: 225

Autism Spectrum Disorder (ASD) is a group of neurodevelopmental disabilities that are not curable but may be ameliorated by early interventions. We gathered early-detected ASD datasets relating to toddlers, children, adolescents and adults, and applied several feature transformation methods, includi...

Life SciencesNeuroscienceCognitive NeuroscienceOpen Access
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Support for a possible schizophrenia vulnerability locus in region 5q22–31 in Irish families

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Richard E. Straub, C J MacLean, F. Anthony O’Neill, Dermot Walsh et al.

Journal: Molecular PsychiatryYear: 1997Citations: 190

In our genome scan for schizophrenia genes in 265 Irish pedigrees, marker D5S818 in 5q22 produced the second best result of the first 223 markers tested (P = 0.002). We then tested an additional 13 markers and the evidence suggests the presence of a vulnerability locus for schizophrenia in region 5q...

Health SciencesMedicinePsychiatry and Mental health
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Additional support for schizophrenia linkage on chromosomes 6 and 8: A multicenter study

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Dieter B. Wildenauer, Sibylle G. Schwab, Margot Albus, Joachim Hallmayer et al.

Journal: American Journal of Medical GeneticsYear: 1996Citations: 186

In response to reported schizophrenia linkage findings on chromosomes 3, 6 and 8, fourteen research groups genotyped 14 microsatellite markers in an unbiased, collaborative (New) sample of 403-567 informative pedigrees per marker, and in the Original sample which produced each finding (the Johns Hop...

Life SciencesBiochemistry, Genetics and Molecular BiologyGenetics
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Autism Spectrum disorders (ASD) in South Asia: a systematic review

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Mohammad Didar Hossain, Helal Uddin Ahmed, MM Jalal Uddin, Waziul Alam Chowdhury et al.

Journal: BMC PsychiatryYear: 2017Citations: 177

BACKGROUND: Autism spectrum disorders (ASD) are a group of complex neurodevelopmental disorders. The prevalence of ASD in many South Asian countries is still unknown. The aim of this study was to systematically review available epidemiological studies of ASD in this region to identify gaps in our cu...

Life SciencesNeuroscienceCognitive NeuroscienceOpen Access
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Reduced scent marking and ultrasonic vocalizations in the BTBR T+tf/J mouse model of autism

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Markus Wöhr, Florence Roullet, Jacqueline N. Crawley

Journal: Genes Brain & BehaviorYear: 2010Citations: 176

Qualitative impairments in communication, such as delayed language and poor interactive communication skills, are fundamental to the diagnosis of autism. Investigations into social communication in adult BTBR T+tf/J (BTBR) mice are needed to determine whether this inbred strain incorporates phenotyp...

Life SciencesNeuroscienceCognitive Neuroscience
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Computer-Presented Video Models to Teach Generative Spelling to a Child with an Autism Spectrum Disorder

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Elisabeth M. Kinney, Joseph Vedora, Robert Stromer

Journal: Journal of Positive Behavior InterventionsYear: 2003Citations: 161

We examined the use of computer video models and video rewards to teach generative spelling to a child with an autism spectrum disorder. In Phase 1, Ana viewed video models of her teacher writing target words. After Ana wrote the words correctly, she watched videos of play routines unique to each tr...

Life SciencesNeuroscienceCognitive Neuroscience
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Teaching Play Activities to Preschool Children with Disabilities

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Karin Lifter, Beth Sulzer‐Azároff, Stephen R. Anderson, Glynnis Edwards Cowdery

Journal: Journal of Early InterventionYear: 1993Citations: 140

The purpose of this study was to determine whether three preschool children with autism or autistic-like behaviors would learn and generalize pretend play activities targeted at two different play levels—a developmentally appropriate (DA) level and an age appropriate (AA) leve—-differently. The chil...

Life SciencesNeuroscienceCognitive Neuroscience
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Improved Transfer-Learning-Based Facial Recognition Framework to Detect Autistic Children at an Early Stage

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Tania Akter, Mohammad Hanif Ali, Md. Imran Khan, Md. Shahriare Satu et al.

Journal: Brain SciencesYear: 2021Citations: 138

Autism spectrum disorder (ASD) is a complex neuro-developmental disorder that affects social skills, language, speech and communication. Early detection of ASD individuals, especially children, could help to devise and strategize right therapeutic plan at right time. Human faces encode important mar...

Life SciencesNeuroscienceCognitive NeuroscienceOpen Access
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Genome-wide scans of three independent sets of 90 Irish multiplex schizophrenia families and follow-up of selected regions in all families provides evidence for multiple susceptibility genes

Verified

Richard E. Straub, C J MacLean, Yunlong Ma, Bradley T. Webb et al.

Journal: Molecular PsychiatryYear: 2002Citations: 133

From our linkage study of Irish families with a high density of schizophrenia, we have previously reported evidence for susceptibility genes in regions 5q21-31, 6p24-21, 8p22-21, and 10p15-p11. In this report, we describe the cumulative results from independent genome scans of three a priori random ...

Life SciencesNeuroscienceCognitive NeuroscienceOpen Access
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A Monitoring System for Patients of Autism Spectrum Disorder Using Artificial Intelligence

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Md. Hasan Al Banna, Tapotosh Ghosh, Kazi Abu Taher, M. Shamim Kaiser et al.

Journal: Lecture notes in computer scienceYear: 2020Citations: 129
Life SciencesNeuroscienceCognitive Neuroscience
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A Machine Learning Framework for Early-Stage Detection of Autism Spectrum Disorders

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S. M. Mahedy Hasan, Md Palash Uddin, Md. Al Mamun, Muhammad Imran Sharif et al.

Journal: IEEE AccessYear: 2022Citations: 128

Autism Spectrum Disorder (ASD) is a type of neurodevelopmental disorder that affects the everyday life of affected patients. Though it is considered hard to completely eradicate this disease, disease severity can be mitigated by taking early interventions. In this paper, we propose an effective fram...

Life SciencesNeuroscienceCognitive NeuroscienceOpen Access
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