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16+ results
Field: Berberine and alkaloids research

Coriandrum sativum L.: A Review on Ethnopharmacology, Phytochemistry, and Cardiovascular Benefits

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Nisa Najibah Mahleyuddin, Said Moshawih, Long Chiau Ming, Hanis Hanum Zulkifly et al.

Journal: Molecules
Year: 2021
Citations: 396

Coriandrum sativum (C. sativum), belonging to the Apiaceae (Umbelliferae) family, is widely recognized for its uses in culinary and traditional medicine. C. sativum contains various phytochemicals such as polyphenols, vitamins, and many phytosterols, which account for its properties including antica...

Life SciencesAgricultural and Biological SciencesPlant ScienceOpen Access
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Berberine as a Potential Anticancer Agent: A Comprehensive Review

Verified

Abdur Rauf, Tareq Abu‐Izneid, Anees Ahmed Khalil, Muhammad Imran et al.

Journal: MoleculesYear: 2021Citations: 283

Berberine (BBR), a potential bioactive agent, has remarkable health benefits. A substantial amount of research has been conducted to date to establish the anticancer potential of BBR. The present review consolidates salient information concerning the promising anticancer activity of this compound. T...

Health SciencesMedicinePharmacologyOpen Access
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Randomized Controlled Trial of Berberine Sulfate Therapy for Diarrhea Due to Enterotoxigenic Escherichia coli and Vibrio cholerae

Verified

Golam Rabbani, Thomas Butler, Joseph A. Knight, S. C. Sanyal et al.

Journal: The Journal of Infectious DiseasesYear: 1987Citations: 215

To evaluate the antisecretory activity of berberine sulfate (BS), we studied 165 adult patients with acute diarrhea due to enterotoxigenic Escherichia coli (ETEC) and Vibrio cholerae in randomized controlled trials. In patients with ETEC diarrhea who received 400 mg of BS in a single oral dose, the ...

Life SciencesBiochemistry, Genetics and Molecular BiologyEndocrinology
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Plant-Based Indole Alkaloids: A Comprehensive Overview from a Pharmacological Perspective

Verified

Faisal Omar, Abu Montakim Tareq, Ali Alqahtani, Kuldeep Dhama et al.

Journal: MoleculesYear: 2021Citations: 169

Plant-based indole alkaloids are very rich in pharmacological activities, and the indole nucleus is considered to contribute greatly to these activities. This review's fundamental objective is to summarize the pharmacological potential of indole alkaloids that have been derived from plants and provi...

Life SciencesPharmacology, Toxicology and PharmaceuticsPharmacologyOpen Access
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Papaverine: A Miraculous Alkaloid from Opium and Its Multimedicinal Application

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Sania Ashrafi, Safaet Alam, Arifa Sultana, Asef Raj et al.

Journal: MoleculesYear: 2023Citations: 69

L. Although it lacks analgesic effects and is unrelated to the compounds in the morphine class, it is a peripheral vasodilator and has a direct effect on vessels. It is reported to inhibit the cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) phosphodiesterase in smooth...

Health SciencesMedicinePharmacologyOpen Access
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The effect of vildagliptin relative to sulphonylureas in Muslim patients with type 2 diabetes fasting during Ramadan: the <scp>VIRTUE</scp> study

Verified

Monira Alarouj, Ahmed Hassoun, R. Medlej, Md Faruque Pathan et al.

Journal: International Journal of Clinical PracticeYear: 2013Citations: 67

AIMS: To assess, in a real-world setting, the effect of vildagliptin compared with sulphonylurea (SU) treatment on hypoglycaemia in Muslim patients with type 2 diabetes mellitus (T2DM) fasting during Ramadan. METHODS: This multinational, non-interventional study, conducted in Asia and the Middle Eas...

Health SciencesMedicinePhysiologyOpen Access
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Health is a spiritual thing: perspectives of health care professionals and female Somali and Bangladeshi women on the health impacts of fasting during Ramadan

Verified

Rubini Pathy, Kelsey E. Mills, Sharon Gazeley, Andrea Ridgley et al.

Journal: Ethnicity and HealthYear: 2010Citations: 62

OBJECTIVE: To explore perspectives of health care professionals and female Somali and Bangladeshi Muslim women on practices related to fasting during Ramadan, the impact of fasting on health and the role of health professionals during Ramadan. DESIGN: A cross-sectional qualitative study was conducte...

Health SciencesMedicinePhysiology
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Fasting during Ramadan in adolescents with diabetes

Verified

Bedowra Zabeen, Samin Tayyeb, Biplob Benarjee, Abdul Baki et al.

Journal: Indian Journal of Endocrinology and MetabolismYear: 2014Citations: 60

BACKGROUND: Fasting (Sawm) during Ramadan, one of the five pillars of Islam is obligatory for all healthy adult and adolescent Muslims from the age of 12 years. Some children with diabetes, despite their exemption insist on fasting in Ramadan. We evaluated the safety of fasting among children with t...

Health SciencesMedicinePhysiologyOpen Access
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Therapeutic use of Adhatoda vasica

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Md. Tofazzal Hossain, Md Obydul Hoq

Journal: Asian Journal of Medical and Biological ResearchYear: 2016Citations: 54

Adhatoda vasica Nees belonging to family Acanthaceae, commonly known as Adosa, is found many regions of India and throughout the world, with a multitude of uses in traditional Unani and Ayurvedic systems of medicine. It is also called “Vasaka”. It is a well-known herb in indigenous systems of medici...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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A comprehensive evaluation of the therapeutic potential of silibinin: a ray of hope in cancer treatment

Verified

Pantha Prodip Ray, Mohammad Ashraful Islam, Mohammad Safiqul Islam, Aixia Han et al.

Journal: Frontiers in PharmacologyYear: 2024Citations: 53

Natural compounds hold promise in the search for cancer therapies due to their unique chemical structures and combinations that may effectively combat cancer while minimizing toxicity and side effects compared to conventional treatments. Silibinin, a natural lignan, has been found to possess strong ...

Health SciencesMedicinePulmonary and Respiratory MedicineOpen Access
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Therapeutic potential of indole alkaloids in respiratory diseases: A comprehensive review

Verified

Saikat Mitra, Shajuthi Rahman Prova, Sifat Ara Sultana, Rajib Das et al.

Journal: PhytomedicineYear: 2021Citations: 50

Background Indole alkaloids are very promising for potential therapeutic purposes and appear to be particularly effective against respiratory diseases. Several experimental studies have been performed, both in vivo and in vitro, to evaluate the effectiveness of indole alkaloids for the management of...

Life SciencesPharmacology, Toxicology and PharmaceuticsPharmacology
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Targeting Autophagy with Natural Products as a Potential Therapeutic Approach for Cancer

Verified

Md. Abdul Alim Al‐Bari, Yuko Ito, Samrein B. M. Ahmed, Nada Radwan et al.

Journal: International Journal of Molecular SciencesYear: 2021Citations: 49

Macro-autophagy (autophagy) is a highly conserved eukaryotic intracellular process of self-digestion caused by lysosomes on demand, which is upregulated as a survival strategy upon exposure to various stressors, such as metabolic insults, cytotoxic drugs, and alcohol abuse. Paradoxically, autophagy ...

Health SciencesMedicineEpidemiologyOpen Access
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Antiulcer principle from Zingiber montanum

Verified

Mohammad Al‐Amin, Gazi Nurun Nahar Sultana, Chowdhury Faiz Hossain

Journal: Journal of EthnopharmacologyYear: 2012Citations: 49

Ethnopharmacological relevance Rhizome of Zingiber montanum has been extensively used as a folk medicine to ameliorate peptic ulcer at northern part of Bangladesh. Aim of the study To identify the antiulcer principle of the MeOH extract of the rhizome of Zingiber montanum by an ex vivo bioassay guid...

Life SciencesPharmacology, Toxicology and PharmaceuticsPharmacology
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Hirsutine, an Emerging Natural Product with Promising Therapeutic Benefits: A Systematic Review

Verified

Md. Shimul Bhuia, Polrat Wilairatana, Jannatul Ferdous, Raihan Chowdhury et al.

Journal: MoleculesYear: 2023Citations: 48

Fruits and vegetables are used not only for nutritional purposes but also as therapeutics to treat various diseases and ailments. These food items are prominent sources of phytochemicals that exhibit chemopreventive and therapeutic effects against several diseases. Hirsutine (HSN) is a naturally occ...

Life SciencesPharmacology, Toxicology and PharmaceuticsPharmacologyOpen Access
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Cardiac glycoside cerberin exerts anticancer activity through PI3K/AKT/mTOR signal transduction inhibition

Verified

Md Shahadat Hossan, Zi-Yang Chan, Hilary M. Collins, Fiona Natalia Shipton et al.

Journal: Cancer LettersYear: 2019Citations: 46

Natural products possess a significant role in anticancer therapy and many currently-used anticancer drugs are of natural origin. Cerberin (CR), a cardenolide isolated from the fruit kernel of Cerbera odollam, was found to potently inhibit cancer cell growth (GI50 values 60% bioavailability and rapi...

Health SciencesMedicinePharmacologyOpen Access
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