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16+ results
Field: Biophysics

A systematic review on silver nanoparticles-induced cytotoxicity: Physicochemical properties and perspectives

Verified

Mahmuda Akter, Md. Tajuddin Sikder, Md. Mostafizur Rahman, A. K. M. Atique Ullah et al.

Journal: Journal of Advanced Research
Year: 2017
Citations: 1193

With the development of nanotechnology, silver nanoparticles (Ag-NPs) have become one of the most in-demand nanoparticles owing to their exponential number of uses in various sectors. The increased use of Ag-NPs-enhanced products may result in an increased level of toxicity affecting both the enviro...

Physical SciencesMaterials ScienceMaterials ChemistryOpen Access
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Stimuli-responsive polymeric nanocarriers for the controlled transport of active compounds: Concepts and applications

Verified

Emanuel Fleige, Mohiuddin Quadir, Rainer Haag

Journal: Advanced Drug Delivery ReviewsYear: 2012Citations: 1097

The use of polymeric nanocarriers to transport active compounds like small-molecular drugs, peptides, or genes found an increased attention throughout the different fields of natural sciences. Not only that these nanocarriers enhance the properties of already existing drugs in terms of solubility, b...

Physical SciencesMaterials SciencePolymers and Plastics
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Responses of Plant Proteins to Heavy Metal Stress—A Review

Verified

Md. Kamrul Hasan, Yuan Cheng, Mukesh Kumar Kanwar, Xianyao Chu et al.

Journal: Frontiers in Plant ScienceYear: 2017Citations: 429

Plants respond to environmental pollutants such as heavy metal(s) by triggering the expression of genes that encode proteins involved in stress response. Toxic metal ions profoundly affect the cellular protein homeostasis by interfering with the folding process and aggregation of nascent or non-nati...

Health SciencesNursingNutrition and DieteticsOpen Access
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Effects of Degeneration on the Biphasic Material Properties of Human Nucleus Pulposus in Confined Compression

Verified

Wade Johannessen, Dawn M. Elliott

Journal: SpineYear: 2005Citations: 246

STUDY DESIGN: The biphasic compressive material properties of normal and degenerate human nucleus pulposus tissue were measured in confined compression. OBJECTIVES: The objective of this study was to determine the effects of degeneration and age on the mechanical properties of human nucleus pulposus...

Health SciencesMedicinePathology and Forensic Medicine
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Melatonin-mediated photosynthetic performance of tomato seedlings under high-temperature stress

Verified

Mohammad Shah Jahan, Guo ShiRong, Jin Sun, Sheng Shu et al.

Journal: Plant Physiology and BiochemistryYear: 2021Citations: 241

Photosynthesis is a fundamental biosynthetic process in plants that can enhance carbon absorption and increase crop productivity. Heat stress severely inhibits photosynthetic efficiency. Melatonin is a bio-stimulator capable of regulating diverse abiotic stress tolerances. However, the underlying me...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular Biology
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Cytotoxic effects of polystyrene nanoplastics with different surface functionalization on human HepG2 cells

Verified

Yixin He, Jing Li, Jiancheng Chen, Xiaojun Miao et al.

Journal: The Science of The Total EnvironmentYear: 2020Citations: 217

Nanoplastics in the environment lead to the human exposure to these particles. However, the consequences of this exposure are not yet fully understood. Here, the cytotoxicity of polystyrene nanoparticles (PS-NPs) with a uniform size (50 nm) but distinct surface functionalization (pristine polystyren...

Physical SciencesEnvironmental SciencePollution
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Silicon in mitigation of abiotic stress-induced oxidative damage in plants

Verified

Mohammad Golam Mostofa, Md. Mezanur Rahman, Md. Mesbah Uddin Ansary, Sanjida Sultana Keya et al.

Journal: Critical Reviews in BiotechnologyYear: 2021Citations: 204

Accumulation of reactive oxygen species (ROS), and their destructive effects on cellular organelles are the hallmark features of plants exposed to abiotic stresses. Plants are well-equipped with defensive mechanisms like antioxidant systems to deal with ROS-induced oxidative stress. Silicon has been...

Life SciencesAgricultural and Biological SciencesPlant Science
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Construction of an enzyme-free concatenated DNA circuit for signal amplification and intracellular imaging

Verified

Huimin Wang, Chunxiao Li, Xiaoqing Liu, Xiang Zhou et al.

Journal: Chemical ScienceYear: 2018Citations: 203

A rationally and modularly engineered two-layered CHA–HCR circuit was constructed for amplified biosensing and bioimaging with high performance.

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Silicate reduces cadmium uptake into cells of wheat

Verified

Maria Greger, Ahmad Humayan Kabir, Tommy Landberg, Pooja Jha Maity et al.

Journal: Environmental PollutionYear: 2015Citations: 192

Cadmium (Cd) is a health threat all over the world and high Cd content in wheat causes high Cd intake. Silicon (Si) decreases cadmium content in wheat grains and shoot. This work investigates whether and how silicate (Si) influences cadmium (Cd) uptake at the cellular level in wheat. Wheat seedlings...

Life SciencesAgricultural and Biological SciencesPlant Science
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Alginate‐Polylysine Microcapsules of Controlled Membrane Molecular Weight Cutoff for Mammalian Cell Culture Engineering

Verified

G. A. King, A. J. Daugulis, P. Faulkner, Mattheus F. A. Goosen

Journal: Biotechnology ProgressYear: 1987Citations: 184

Abstract The search for more productive mammalian cell culture techniques has been primarily driven by the need to increase both the cell density and product concentration. In the technique used in our laboratory, microencapsulation, hybridoma cells were grown and monoclonal antibody was entrapped w...

Health SciencesMedicineSurgery
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Cell type-dependent uptake, localization, and cytotoxicity of 1.9 nm gold nanoparticles

Verified

Jonathan A. Coulter

Journal: International Journal of NanomedicineYear: 2012Citations: 183

BACKGROUND: This follow-up study aims to determine the physical parameters which govern the differential radiosensitization capacity of two tumor cell lines and one immortalized normal cell line to 1.9 nm gold nanoparticles. In addition to comparing the uptake potential, localization, and cytotoxici...

Health SciencesMedicinePulmonary and Respiratory MedicineOpen Access
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3C–SiC Nanocrystals as Fluorescent Biological Labels

Verified

Jiyang Fan, Hongxia Li, Jiang Jiang, Leo K.Y. So et al.

Journal: SmallYear: 2008Citations: 178

Silicon carbide nanocrystals are water-soluble, chemically inert, and highly fluorescent, and they may be idealas biological labels. After the uptake of3C–SiC nanocrystals, human fetal osteoblast (hFOB) cells exhibit brightgreen–yellow fluorescence (see image).The nanoparticles show high resistancea...

Physical SciencesMaterials ScienceMaterials ChemistryOpen Access
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Fibulin-5/DANCE has an elastogenic organizer activity that is abrogated by proteolytic cleavage in vivo

Verified

Maretoshi Hirai, Tetsuya Ohbayashi, Masahito Horiguchi, Katsuya Okawa et al.

Journal: The Journal of Cell BiologyYear: 2007Citations: 165

Elastic fibers are required for the elasticity and integrity of various organs. We and others previously showed that fibulin-5 (also called developing arteries and neural crest EGF-like [DANCE] or embryonic vascular EGF-like repeat-containing protein [EVEC]) is indispensable for elastogenesis by stu...

Life SciencesBiochemistry, Genetics and Molecular BiologyGeneticsOpen Access
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Identification of the region of non‐Aβ component (NAC) of Alzheimer's disease amyloid responsible for its aggregation and toxicity

Verified

Angela M. Bodles, David J. S. Guthrie, Brett Greer, G. Brent Irvine

Journal: Journal of NeurochemistryYear: 2001Citations: 151

The non-beta-amyloid (Abeta) component of Alzheimer's disease amyloid (NAC) and its precursor alpha-synuclein have been linked to amyloidogenesis in several neurodegenerative diseases. NAC and alpha-synuclein both form beta-sheet structures upon ageing, aggregate to form fibrils, and are neurotoxic....

Health SciencesMedicinePhysiologyOpen Access
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Dynamic Compression Effects on Intervertebral Disc Mechanics and Biology

Verified

Casey L. Korecki, Jeffrey J. MacLean, James C. Iatridis

Journal: SpineYear: 2008Citations: 137

STUDY DESIGN: A bovine intervertebral disc organ culture model was used to study the effect of dynamic compression magnitude on mechanical behavior and measurement of biosynthesis rate, cell viability, and mRNA expression. OBJECTIVE: The objective of this study was to examine the effect of loading m...

Health SciencesMedicinePathology and Forensic MedicineOpen Access
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