Susan Walker, Theodore D. Wachs, Sally Grantham‐McGregor, Maureen M. Black et al.
Inequality between and within populations has origins in adverse early experiences. Developmental neuroscience shows how early biological and psychosocial experiences affect brain development. We previously identified inadequate cognitive stimulation, stunting, iodine deficiency, and iron-deficiency...
Anne CC Lee, Joanne Katz, Hannah Blencowe, Simon Cousens et al.
BACKGROUND: National estimates for the numbers of babies born small for gestational age and the comorbidity with preterm birth are unavailable. We aimed to estimate the prevalence of term and preterm babies born small for gestational age (term-SGA and preterm-SGA), and the relation to low birthweigh...
Honor Bixby, James Bentham, Bin Zhou, Mariachiara Di Cesare et al.
Abstract Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities 1,2 . This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity 3–6 . Here we use 2...
Victoria Miller, Andrew Mente, Mahshid Dehghan, Sumathy Rangarajan et al.
BACKGROUND The association between intake of fruits, vegetables, and legumes with cardiovascular disease and deaths has been investigated extensively in Europe, the USA, Japan, and China, but little or no data are available from the Middle East, South America, Africa, or south Asia. METHODS We did a...
Georg Ehret, Teresa Ferreira, Daniel I. Chasman, Anne Jackson et al.
To dissect the genetic architecture of blood pressure and assess effects on target organ damage, we analyzed 128,272 SNPs from targeted and genome-wide arrays in 201,529 individuals of European ancestry, and genotypes from an additional 140,886 individuals were used for validation. We identified 66 ...
Norihiro Kato, CARDIo GRAMplusCD, LifeLines Cohort Study, Marie Loh et al.
We carried out a trans-ancestry genome-wide association and replication study of blood pressure phenotypes among up to 320,251 individuals of East Asian, European and South Asian ancestry. We find genetic variants at 12 new loci to be associated with blood pressure (P = 3.9 × 10−11 to 5.0 × 10−21). ...
Tahmeed Ahmed, Muttaquina Hossain, Kazi Istiaque Sanin
Maternal and child undernutrition and micronutrient deficiencies affect approximately half of the world's population. These conditions include intrauterine growth restriction (IUGR), low birth weight, protein-energy malnutrition, chronic energy deficit of women, and micronutrient deficiencies. Altho...
Aneire Khan, Andrew Ireson, Sari Kovats, Sontosh Kumar Mojumder et al.
Background: Drinking water from natural sources in coastal Bangladesh has become contaminated by varying degrees of salinity due to saltwater intrusion from rising sea levels, cyclone and storm surges and upstream withdrawal of freshwater. Objective: Our objective was to estimate salt intake from dr...
Verónica Miguel, Jessica Tituaña, J. Ignacio Herrero, Laura Herrero et al.
Chronic kidney disease (CKD) remains a major epidemiological, clinical, and biomedical challenge. During CKD, renal tubular epithelial cells (TECs) present a persistent inflammatory and profibrotic response. Fatty acid oxidation (FAO), the main source of energy for TECs, is reduced in kidney fibrosis...
Muaz Rahman, Tamanna Howlader, Mohammad Shahed Masud, Mohammad Lutfor Rahman
BACKGROUND: Malnutrition in children under five years remains a significant problem in Bangladesh, despite substantial socio-economic progress and a decade of interventions aimed at improving it. Although several studies have been conducted to identify the important risk factors of malnutrition, non...
Daniel Roth, Shaun K. Morris, Stanley Zlotkin, Alison D. Gernand et al.
BACKGROUND: It is unclear whether maternal vitamin D supplementation during pregnancy and lactation improves fetal and infant growth in regions where vitamin D deficiency is common. METHODS: We conducted a randomized, double-blind, placebo-controlled trial in Bangladesh to assess the effects of week...
Md Mizanur Rahman, Sarah Krull Abe, Mikiko Kanda, Saki Narita et al.
We conducted a systematic review and meta-analysis of population-based cohort studies of maternal body mass index (BMI) and risk of adverse birth and health outcomes in low- and middle-income countries. PubMed, Embase, CINAHL and the British Nursing Index were searched from inception to February 201...
Aneire Khan, Pauline Franka Denise Scheelbeek, Asma Begum Shilpi, Queenie Chan et al.
BACKGROUND: Hypertensive disorders in pregnancy are among the leading causes of maternal and perinatal death in low-income countries, but the aetiology remains unclear. We investigated the relationship between salinity in drinking water and the risk of (pre)eclampsia and gestational hypertension in ...
Yarlini Balarajan, Eduardo Villamor
Our aims in this study were to examine trends in the prevalence of overweight-obesity and underweight among women of reproductive age in 3 South Asian countries between 1996 and 2006 and to identify sociodemographic correlates of overweight in the most recent survey. Using nationally representative ...
Jane Menken, James Trussell, Susan Watkins
The determinants of age-specific marital fertility rates in non-contracepting populations are discussed and the physiological link between nutrition and reproduction in women who are chronically malnourished rather than famished are examined. Initial attention is directed to menarche and menopause f...