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Field: COVID-19 Clinical Research Studies

COVID-19 and the cardiovascular system

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Ying‐Ying Zheng, Yi‐Tong Ma, Jinying Zhang, Xiang Xie

Journal: Nature Reviews Cardiology 2020
Year:
Citations: 3061

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects host cells through ACE2 receptors, leading to coronavirus disease (COVID-19)-related pneumonia, while also causing acute myocardial injury and chronic damage to the cardiovascular system. Therefore, particular attention should be g...

Health SciencesMedicineInfectious DiseasesOpen Access
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Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study

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Ting Shi, David McAllister, Katherine L. O’Brien, Eric A. F. Simões et al.

Journal: The LancetYear: 2017Citations: 2398

BACKGROUND: We have previously estimated that respiratory syncytial virus (RSV) was associated with 22% of all episodes of (severe) acute lower respiratory infection (ALRI) resulting in 55 000 to 199 000 deaths in children younger than 5 years in 2005. In the past 5 years, major research activity on...

Health SciencesMedicineEpidemiologyOpen Access
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Omicron variant of SARS‐CoV‐2: Genomics, transmissibility, and responses to current COVID‐19 vaccines

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Yusha Araf, F. Akter, Yan‐Dong Tang, Rabeya Fatemi et al.

Journal: Journal of Medical VirologyYear: 2022Citations: 909

Currently, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide as an Omicron variant. This variant is a heavily mutated virus and designated as a variant of concern by the World Health Organization (WHO). WHO cautioned that the Omicron variant of SARS-CoV-2 held a very ...

Health SciencesMedicineInfectious DiseasesOpen Access
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Insights into the Recent 2019 Novel Coronavirus (SARS-CoV-2) in Light of Past Human Coronavirus Outbreaks

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Hossam M. Ashour, Walid F. Elkhatib, Md. Masudur Rahman, Hatem A. Elshabrawy

Journal: PathogensYear: 2020Citations: 627

Coronaviruses (CoVs) are RNA viruses that have become a major public health concern since the Severe Acute Respiratory Syndrome-CoV (SARS-CoV) outbreak in 2002. The continuous evolution of coronaviruses was further highlighted with the emergence of the Middle East Respiratory Syndrome-CoV (MERS-CoV)...

Health SciencesMedicineInfectious DiseasesOpen Access
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Evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as coronavirus disease 2019 (COVID-19) pandemic: A global health emergency

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Thamina Acter, Nizam Uddin, Jagotamoy Das, Afroza Akhter et al.

Journal: The Science of The Total EnvironmentYear: 2020Citations: 591

According to data compiled by researchers at Johns Hopkins University in Baltimore, Maryland, more than two and half million cases of coronavirus disease 2019 (COVID-19), caused by a newly discovered virus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), have been confirmed on Apr...

Health SciencesMedicineRadiology, Nuclear Medicine and ImagingOpen Access
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Role of vitamin D in preventing of COVID-19 infection, progression and severity

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Nurshad Ali

Journal: Journal of Infection and Public HealthYear: 2020Citations: 586

The outbreak of COVID-19 has created a global public health crisis. Little is known about the protective factors of this infection. Therefore, preventive health measures that can reduce the risk of infection, progression and severity are desperately needed. This review discussed the possible roles o...

Health SciencesMedicinePathology and Forensic MedicineOpen Access
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Post-COVID-19 syndrome among symptomatic COVID-19 patients: A prospective cohort study in a tertiary care center of Bangladesh

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Reaz Mahmud, Md Mujibur Rahman, Mohammad Aftab Rassel, Farhana Binte Monayem et al.

Journal: PLoS ONEYear: 2021Citations: 570

BACKGROUND: Post-coronavirus disease (COVID-19) syndrome includes persistence of symptoms beyond viral clearance and fresh development of symptoms or exaggeration of chronic diseases within a month after initial clinical and virological cure of the disease with a viral etiology. We aimed to determin...

Health SciencesMedicineNeurologyOpen Access
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Association of Sex, Age, and Comorbidities with Mortality in COVID-19 Patients: A Systematic Review and Meta-Analysis

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Mohitosh Biswas, Shawonur Rahaman, Tapash Kumar Biswas, Zahirul Haque et al.

Journal: IntervirologyYear: 2020Citations: 513

<b><i>Introduction:</i></b> Although severe acute respiratory syndrome coronavirus-2 infection is causing mortality in considerable proportion of coronavirus disease-2019 (COVID-19) patients, however, evidence for the association of sex, age, and comorbidities on the risk of ...

Health SciencesMedicineInfectious DiseasesOpen Access
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COVID-19 and Bangladesh: Challenges and How to Address Them

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Saeed Anwar, Mohammad Nasrullah, Mohammad Jakir Hosen

Journal: Frontiers in Public HealthYear: 2020Citations: 497

As the coronavirus outbreak quickly surges worldwide, many countries are adopting non-therapeutic preventive measures, which include travel bans, remote office activities, country lockdown, and most importantly, social distancing. However, these measures face challenges in Bangladesh, a lower-middle...

Physical SciencesMathematicsModeling and SimulationOpen Access
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Immune response in COVID-19: A review

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Mohammad Asaduzzaman Chowdhury, Nayem Hossain, Mohammod Abul Kashem, Md. Abdus Shahid et al.

Journal: Journal of Infection and Public HealthYear: 2020Citations: 459

The immune system protects against viruses and diseases and produces antibodies to kill pathogens. This review presents a brief overview of the immune system regarding its protection of the human body from COVID-19; illustrates the process of the immune system, how it works, and its mechanism to fig...

Health SciencesMedicineInfectious DiseasesOpen Access
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Efficacy and Safety of an mRNA-Based RSV PreF Vaccine in Older Adults

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Eleanor Wilson, Jaya Goswami, Abdullah H Baqui, Pablo Alexis Doreski et al.

Journal: New England Journal of MedicineYear: 2023Citations: 439

BACKGROUND: Respiratory syncytial virus (RSV) can cause substantial morbidity and mortality among older adults. An mRNA-based RSV vaccine, mRNA-1345, encoding the stabilized RSV prefusion F glycoprotein, is under clinical investigation. METHODS: In this ongoing, randomized, double-blind, placebo-con...

Health SciencesMedicineEpidemiologyOpen Access
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Elevated level of C‐reactive protein may be an early marker to predict risk for severity of COVID‐19

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Nurshad Ali

Journal: Journal of Medical VirologyYear: 2020Citations: 368

The outbreak of coronavirus disease-2019 (COVID-19) is an emerging global health threat. The healthcare workers are facing challenges in reducing the severity and mortality of COVID-19 across the world. Severe patients with COVID-19 are generally treated in the intensive care unit, while mild or non...

Health SciencesMedicineInfectious DiseasesOpen Access
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Emergence of SARS-CoV-2 Omicron (B.1.1.529) variant, salient features, high global health concerns and strategies to counter it amid ongoing COVID-19 pandemic

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Rekha Khandia, Shailja Singhal, Taha Alqahtani, Mohammad Amjad Kamal et al.

Journal: Environmental ResearchYear: 2022Citations: 320

Since the appearance in the late of December 2019, SARS-CoV-2 is rapidly evolving and mutating continuously, giving rise to various variants with variable degrees of infectivity and lethality. The virus that initially appeared in China later mutated several times, wreaking havoc and claiming many li...

Health SciencesMedicineInfectious DiseasesOpen Access
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Prevalence and Associated Risk Factors of Mortality Among COVID-19 Patients: A Meta-Analysis

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Farha Musharrat Noor, Md. Momin Islam

Journal: Journal of Community HealthYear: 2020Citations: 312

The main aim of this study was to find the prevalence of mortality among hospitalized COVID-19 infected patients and associated risk factors for death. Three electronic databases including PubMed, Science Direct and Google Scholar were searched to identify relevant cohort studies of COVID-19 disease...

Health SciencesMedicineInfectious DiseasesOpen Access
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Pre-existing liver disease is associated with poor outcome in patients with SARS CoV2 infection; The APCOLIS Study (APASL COVID-19 Liver Injury Spectrum Study)

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Shiv Kumar Sarin, Ashok Choudhury, George Lau, Ming‐Hua Zheng et al.

Journal: Hepatology InternationalYear: 2020Citations: 295

Background and aims COVID-19 is a dominant pulmonary disease, with multisystem involvement, depending upon comorbidities. Its profile in patients with pre-existing chronic liver disease (CLD) is largely unknown. We studied the liver injury patterns of SARS-Cov-2 in CLD patients, with or without cirr...

Health SciencesMedicineInfectious DiseasesOpen Access
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