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Field: COVID-19 Clinical Research Studies

Global emerging Omicron variant of SARS-CoV-2: Impacts, challenges and strategies

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Kuldeep Dhama, Firzan Nainu, Andri Frediansyah, Mohd. Iqbal Yatoo et al.

Journal: Journal of Infection and Public Health
Year: 2022
Citations: 257

Newly emerging variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are continuously posing high global public health concerns and panic resulting in waves of coronavirus disease 2019 (COVID-19) pandemic. Depending on the extent of genomic variations, mutations and adaptation, fe...

Health SciencesMedicineInfectious DiseasesOpen Access
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Role of Inflammatory Cytokines in COVID-19 Patients: A Review on Molecular Mechanisms, Immune Functions, Immunopathology and Immunomodulatory Drugs to Counter Cytokine Storm

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Ali A. Rabaan, Shamsah H. Al-Ahmed, Javed Muhammad, Amjad Khan et al.

Journal: VaccinesYear: 2021Citations: 256

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a severe pandemic of the current century. The vicious tentacles of the disease have been disseminated worldwide with unknown complications and repercussions. Advanced COVID-19 syndrome is ...

Health SciencesMedicineInfectious DiseasesOpen Access
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Predictive Data Mining Models for Novel Coronavirus (COVID-19) Infected Patients’ Recovery

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L. J. Muhammad, Md. Milon Islam, Sani Sharif Usman, Safial Islam Ayon

Journal: SN Computer ScienceYear: 2020Citations: 245

Novel coronavirus (COVID-19 or 2019-nCoV) pandemic has neither clinically proven vaccine nor drugs; however, its patients are recovering with the aid of antibiotic medications, anti-viral drugs, and chloroquine as well as vitamin C supplementation. It is now evident that the world needs a speedy and...

Health SciencesMedicineRadiology, Nuclear Medicine and ImagingOpen Access
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Impact of age, sex, comorbidities and clinical symptoms on the severity of COVID-19 cases: A meta-analysis with 55 studies and 10014 cases

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Md Abdul Barek, Md. Abdul Aziz, Mohammad Safiqul Islam

Journal: HeliyonYear: 2020Citations: 243

PURPOSE: Severe acute respiratory coronavirus 2 (SARS-CoV-2) cases are overgrowing globally and now become a pandemic. A meta-analysis was conducted to evaluate the impact of age, sex, comorbidities, and clinical characteristics on the severity of COVID-19 to help diagnose and evaluate the current o...

Health SciencesMedicineInfectious DiseasesOpen Access
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Efficacy, Immunogenicity and Safety of COVID-19 Vaccines: A Systematic Review and Meta-Analysis

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Nadim Sharif, Khalid J. Alzahrani, Shamsun Nahar Ahmed, Shuvra Kanti Dey

Journal: Frontiers in ImmunologyYear: 2021Citations: 241

There is a significant research gap in meta-analysis on the efficacy and safety of coronavirus disease 2019 (COVID-19) vaccines. This study analyzed the efficacy of COVID-19 vaccines. Published phase I, phase II, and phase III trials analyzing safety and immunogenicity and phase III randomized clini...

Health SciencesMedicineInfectious DiseasesOpen Access
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Global burden of acute lower respiratory infection associated with human metapneumovirus in children under 5 years in 2018: a systematic review and modelling study

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Xin Wang, You Li, Maria Deloria Knoll, Shabir A. Madhi et al.

Journal: The Lancet Global HealthYear: 2020Citations: 222

BACKGROUND: Human metapneumovirus is a common virus associated with acute lower respiratory infections (ALRIs) in children. No global burden estimates are available for ALRIs associated with human metapneumovirus in children, and no licensed vaccines or drugs exist for human metapneumovirus infectio...

Health SciencesMedicineEpidemiologyOpen Access
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Reconstructing the early global dynamics of under-ascertained COVID-19 cases and infections

Verified

Timothy Russell, Nick Golding, Joel Hellewell, Sam Abbott et al.

Journal: BMC MedicineYear: 2020Citations: 217

BACKGROUND: Asymptomatic or subclinical SARS-CoV-2 infections are often unreported, which means that confirmed case counts may not accurately reflect underlying epidemic dynamics. Understanding the level of ascertainment (the ratio of confirmed symptomatic cases to the true number of symptomatic ind...

Physical SciencesMathematicsModeling and SimulationOpen Access
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Epidemiology of COVID-19 infection in young children under five years: A systematic review and meta-analysis

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Mejbah Bhuiyan, Eunice Stiboy, Md Zakiul Hassan, Mei Chan et al.

Journal: VaccineYear: 2020Citations: 204

Introduction Emerging evidence suggests young children are at greater risk of COVID-19 infection than initially predicted. However, a comprehensive understanding of epidemiology of COVID-19 infection in young children under five years, the most at-risk age-group for respiratory infections, remain un...

Health SciencesMedicineInfectious DiseasesOpen Access
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Tackling the Covid-19 Pandemic: The Bangladesh Perspective

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Taimur Islam, Anup Kumar Talukder, Md. Nurealam Siddiqui, Tofazzal Islam

Journal: Journal of public health researchYear: 2020Citations: 171

An outbreak of a COVID-19 pandemic disease, caused by a novel coronavirus SARS-CoV-2, has posed a serious threat to global human health. Bangladesh has also come under the attack of this viral disease. Here, we aimed to describe the responses of Bangladesh to tackle the COVID-19, particularly on how...

Health SciencesMedicineInfectious DiseasesOpen Access
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A machine learning model to identify early stage symptoms of SARS-Cov-2 infected patients

Verified

Md. Martuza Ahamad, Sakifa Aktar, Md. Rashed-Al-Mahfuz, Shahadat Uddin et al.

Journal: Expert Systems with ApplicationsYear: 2020Citations: 168

Highlights • Machine learning was used to develop models to predict COVID-19 positive patient.• Features were extracted from patient data using string matching algorithms.• Constructed a novel dataset from unstructured hospitalized patient information.• Used descriptive statistical analysis for freq...

Health SciencesMedicineRadiology, Nuclear Medicine and ImagingOpen Access
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Silent hypoxia in COVID-19: pathomechanism and possible management strategy

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Ahsab Rahman, Tahani Tabassum, Yusha Araf, Abdullah Al Nahid et al.

Journal: Molecular Biology ReportsYear: 2021Citations: 153

The novel coronavirus disease 2019 (COVID-19) has become a severe health issue, especially to the patients who develop silent hypoxia condition after SARS-CoV-2 infection. Due to the lack of dyspnoea and extremely low oxygen saturation level, these patients are at exceptionally higher risk. Although...

Health SciencesMedicineNeurologyOpen Access
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Effects of underlying morbidities on the occurrence of deaths in COVID-19 patients: A systematic review and meta-analysis

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Md. Mostaured Ali Khan, Md Nuruzzaman Khan, Md. Golam Mustagir, Juwel Rana et al.

Journal: Journal of Global HealthYear: 2020Citations: 140

BACKGROUND: Coronavirus disease 2019 (COVID-19), the most hectic pandemic of the era, is increasing exponentially and taking thousands of lives worldwide. This study aimed to assess the prevalence of pre-existing comorbidities among COVID-19 patients and their mortality risks with each category of p...

Health SciencesMedicineInfectious DiseasesOpen Access
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COVID-19 pandemic and addiction: Current problems and future concerns

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Sujita Kumar Kar, S. M. Yasir Arafat, Pawan Sharma, Ayushi Dixit et al.

Journal: Asian Journal of PsychiatryYear: 2020Citations: 136
Social SciencesPsychologyClinical PsychologyOpen Access
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Long COVID‐19: Objectifying most self‐reported neurological symptoms

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Julia Bungenberg, Karen Humkamp, Christian Hohenfeld, Marcus Immanuel Rust et al.

Journal: Annals of Clinical and Translational NeurologyYear: 2022Citations: 132

Abstract Objectives We aimed to objectify and compare persisting self‐reported symptoms in initially hospitalized and non‐hospitalized patients after infection with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) by applying clinical standardized measures. Methods We conducted a cross‐s...

Health SciencesMedicineNeurologyOpen Access
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Transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to animals: an updated review

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Sina Salajegheh Tazerji, Phelipe Magalhães Duarte, Parastoo Rahimi, Fatemeh Shahabinejad et al.

Journal: Journal of Translational MedicineYear: 2020Citations: 130

COVID-19 caused by a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) originated in Wuhan (Hubei province, China) during late 2019. It has spread across the globe affecting nearly 21 million people with a toll of 0.75 million deaths and restricting the movement of most of the world...

Health SciencesMedicineInfectious DiseasesOpen Access
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