Md. Jakaria, Shofiul Azam, Md. Ezazul Haque, Song-Hee Jo et al.
Taurine is a sulfur-containing amino acid and known as semi-essential in mammals and is produced chiefly by the liver and kidney. It presents in different organs, including retina, brain, heart and placenta and demonstrates extensive physiological activities within the body. In the several disease m...
Bashar Emon, Jessica Bauer, Yasna Jain, Barbara Jung et al.
The role of tumor microenvironment in cancer progression is gaining significant attention. It is realized that cancer cells and the corresponding stroma co-evolve with time. Cancer cells recruit and transform the stromal cells, which in turn remodel the extra cellular matrix of the stroma. This comp...
Pierre Gladieux, Bradford Condon, Sébastien Ravel, Darren M. Soanes et al.
ABSTRACT Delineating species and epidemic lineages in fungal plant pathogens is critical to our understanding of disease emergence and the structure of fungal biodiversity and also informs international regulatory decisions. Pyricularia oryzae (syn. Magnaporthe oryzae ) is a multihost pathogen that ...
Georgia Drakakaki, Wilhelmina van de Ven, Songqin Pan, Yansong Miao et al.
The endomembrane system is a complex and dynamic intracellular trafficking network. It is very challenging to track individual vesicles and their cargos in real time; however, affinity purification allows vesicles to be isolated in their natural state so that their constituent proteins can be identi...
Yinfei Tan, Nathalie Dourdin, Chao Wu, Teresa De Veyra et al.
Ubiquitously expressed μ- and m-calpain proteases are implicated in development and apoptosis. They consist of 80-kDa catalytic subunits encoded by the capn1 and capn2 genes, respectively, and a common 28-kDa regulatory subunit encoded by the capn4 gene. The regulatory subunit is required to maintai...
L. D. Wright, H. R. Skegs
The microbiological determination of biotin, using Lactobacillus arabinosus as the test organism, was studied. The existence of a water-soluble, avidin-combinable, form of biotin in certain enzymatically prepared materials which is available to L. casei, but not to L. arabinosus, was demonstrated. W...
Mahmud Tareq Hassan Khan, M. Iqbal Choudhary, Khalid Mohammed Khan, Mubeen Rani et al.
Here the tyrosinase inhibition studies of library of 2,5-disubstituted-1,3,4-oxadiazoles have been reported and their structure-activity relationship (SAR) also have been discussed. The library of the oxadiazoles was synthesized under the microwave irradiation and was structures of these were charac...
David M. Geiser, Abdullah M. S. Al‐Hatmi, Takayuki Aoki, Tsutomu Arie et al.
Scientific communication is facilitated by a data-driven, scientifically sound taxonomy that considers the end-user’s needs and established successful practice. In 2013, the Fusarium community voiced near unanimous support for a concept of Fusarium that represented a clade comprising all agricultura...
Stacy Visser, Xiaolong Yang
Accumulating evidence points to the LATS (Large Tumor Suppressor) family of human tumor suppressors (LATS1 and LATS2) as new resident governors of cellular homeostasis. Loss of function of either LATS1 or LATS2 leads to a variety of tumor types including soft tissue sarcomas, leukemia, as well as br...
Batiseba Tembo, Rabson M. Mulenga, Suwilanji Sichilima, Kenneth K. M’siska et al.
Wheat blast caused by Magnaporthe oryzae pathotype Triticum (MoT) is a threat to wheat production especially in the warmer-humid environments. In Zambia, wheat blast symptoms were observed for the first time on wheat (Triticum aestivum L.) grown in experimental plots and five farmers' fields in Mpik...
Leonor Gama-Norton, Eva Ferrando, Cristina Ruiz‐Herguido, Zhenyi Liu et al.
Acquisition of the arterial and haemogenic endothelium fates concurrently occur in the aorta-gonad-mesonephros (AGM) region prior to haematopoietic stem cell (HSC) generation. The arterial programme depends on Dll4 and the haemogenic endothelium/HSC on Jag1-mediated Notch1 signalling. How Notch1 dis...
Md. Sahab Uddin, Devesh Tewari, Gaurav Sharma, Md. Tanvir Kabir et al.
Alzheimer's disease (AD) is a progressive neurodegenerative disease involving aggregation of misfolded proteins inside the neuron causing prolonged cellular stress. The neuropathological hallmarks of AD include the formation of senile plaques and neurofibrillary tangles in specific brain regions tha...
Md Monirujjaman, Afroza Ferdouse
Branch chain amino acids (BCAAs) have unique properties with diverse physiological and metabolic roles. They have functions other than simple nutrition. Different diseases including metabolic disease lead to protein loss, especially muscle protein. Supplementation of BCAAs promotes protein synthesis...
Ann E. Kelley
Yuan-Li Tsai, Dat P. Ha, He Zhao, Anthony J. Carlos et al.
The discovery that endoplasmic reticulum (ER) luminal chaperones such as GRP78/BiP can escape to the cell surface upon ER stress where they regulate cell signaling, proliferation, apoptosis, and immunity represents a paradigm shift. Toward deciphering the mechanisms, we report here that, upon ER str...