Joshua A Welsh, Deborah C. I. Goberdhan, Lorraine O’Driscoll, Edit I. Buzás et al.
Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of origin and change the functions and phenotypes of other cells. These features indicate strong biomarker and therapeutic potential and have generated broad interest, as evidenced by the steady year-on-ye...
Mirza Hasanuzzaman, M. H. M. Borhannuddin Bhuyan, Faisal Zulfiqar, Ali Raza et al.
Global climate change and associated adverse abiotic stress conditions, such as drought, salinity, heavy metals, waterlogging, extreme temperatures, oxygen deprivation, etc., greatly influence plant growth and development, ultimately affecting crop yield and quality, as well as agricultural sustaina...
Mirza Hasanuzzaman, Kamrun Nahar, Md. Shahidul Alam, Rajib Roychowdhury et al.
High temperature (HT) stress is a major environmental stress that limits plant growth, metabolism, and productivity worldwide. Plant growth and development involve numerous biochemical reactions that are sensitive to temperature. Plant responses to HT vary with the degree and duration of HT and the ...
Swati Sachdev, Shamim Akhtar Ansari, Mohammad Israil Ansari, Masayuki Fujita et al.
Climate change is an invisible, silent killer with calamitous effects on living organisms. As the sessile organism, plants experience a diverse array of abiotic stresses during ontogenesis. The relentless climatic changes amplify the intensity and duration of stresses, making plants dwindle to survi...
Mirza Hasanuzzaman, M. H. M. Borhannuddin Bhuyan, Taufika Islam Anee, Khursheda Parvin et al.
Reactive oxygen species (ROS) generation is a usual phenomenon in a plant both under a normal and stressed condition. However, under unfavorable or adverse conditions, ROS production exceeds the capacity of the antioxidant defense system. Both non-enzymatic and enzymatic components of the antioxidan...
Mahmuda Akter, Md. Tajuddin Sikder, Md. Mostafizur Rahman, A. K. M. Atique Ullah et al.
With the development of nanotechnology, silver nanoparticles (Ag-NPs) have become one of the most in-demand nanoparticles owing to their exponential number of uses in various sectors. The increased use of Ag-NPs-enhanced products may result in an increased level of toxicity affecting both the enviro...
Muhammad Torequl Islam
Reactive species play an important role in physiological functions. Overproduction of reactive species, notably reactive oxygen (ROS) and nitrogen (RNS) species along with the failure of balance by the body's antioxidant enzyme systems results in destruction of cellular structures, lipids, proteins,...
Mirza Hasanuzzaman, M. H. M. Borhannuddin Bhuyan, Kamrun Nahar, Sharif Hossain et al.
Among the plant nutrients, potassium (K) is one of the vital elements required for plant growth and physiology. Potassium is not only a constituent of the plant structure but it also has a regulatory function in several biochemical processes related to protein synthesis, carbohydrate metabolism, and...
Mohammad Anwar Hossain, Soumen Bhattacharjee, Armin Saed‐Moucheshi, Pingping Qian et al.
Plants are constantly challenged by various abiotic stresses that negatively affect growth and productivity worldwide. During the course of their evolution, plants have developed sophisticated mechanisms to recognize external signals allowing them to respond appropriately to environmental conditions...
Mirza Hasanuzzaman, Md. Rakib Hossain Raihan, Abdul Awal Chowdhury Masud, Khussboo Rahman et al.
The generation of oxygen radicals and their derivatives, known as reactive oxygen species, (ROS) is a part of the signaling process in higher plants at lower concentrations, but at higher concentrations, those ROS cause oxidative stress. Salinity-induced osmotic stress and ionic stress trigger the o...
Uttam Kumar Ghosh, Md. Nahidul Islam, Md. Nurealam Siddiqui, Xiaohuang Cao et al.
Abiotic stresses have a detrimental impact on plant growth and productivity and are a major threat to sustainable crop production in rapidly changing environments. Proline, an important amino acid, plays an important role in maintaining the metabolism and growth of plants under abiotic stress condit...
Md Shaifur Rahman, Naznin Akhtar, Hossen Mohammad Jamil, Rajat Suvra Banik et al.
Transforming growth factor-beta (TGF-β)/bone morphogenetic protein (BMP) plays a fundamental role in the regulation of bone organogenesis through the activation of receptor serine/threonine kinases. Perturbations of TGF-β/BMP activity are almost invariably linked to a wide variety of clinical outcom...
Mirza Hasanuzzaman, M. H. M. Borhannuddin Bhuyan, Khursheda Parvin, Tasnim Farha Bhuiyan et al.
Various environmental stresses singly or in combination generate excess amounts of reactive oxygen species (ROS), leading to oxidative stress and impaired redox homeostasis. Generation of ROS is the obvious outcome of abiotic stresses and is gaining importance not only for their ubiquitous generatio...
Sarvajeet Singh Gill, Naser A. Anjum, Mirza Hasanuzzaman, Ritu Gill et al.
Abiotic stresses such as salinity, drought, clilling, heavy metal are the major limiting factors for crop productivity. These stresses induce the overproduction of reactive oxygen species (ROS) which are highly reactive and toxic, which must be minimized to protect the cell from oxidative damage. Th...
Harrison Specht, Edward Emmott, Aleksandra A. Petelski, R. Gray Huffman et al.
BACKGROUND: Macrophages are innate immune cells with diverse functional and molecular phenotypes. This diversity is largely unexplored at the level of single-cell proteomes because of the limitations of quantitative single-cell protein analysis. RESULTS: To overcome this limitation, we develop SCoPE...