Ian G. Stiell, Catherine M. Clement, R.Douglas McKnight, Robert J. Brison et al.
BACKGROUND: The Canadian C-Spine (cervical-spine) Rule (CCR) and the National Emergency X-Radiography Utilization Study (NEXUS) Low-Risk Criteria (NLC) are decision rules to guide the use of cervical-spine radiography in patients with trauma. It is unclear how the two decision rules compare in terms...
Wade Johannessen, Dawn M. Elliott
STUDY DESIGN: The biphasic compressive material properties of normal and degenerate human nucleus pulposus tissue were measured in confined compression. OBJECTIVES: The objective of this study was to determine the effects of degeneration and age on the mechanical properties of human nucleus pulposus...
Pradeep K. Narotam, Sunil Jose, Narendra Nathoo, Charles Taylon et al.
STUDY DESIGN: Retrospective review of 110 patients undergoing spinal dural repair and regeneration using an onlay, suture-free, 3-dimensional-collagen matrix graft (DuraGen) over an 8-year period (1995-2003). OBJECTIVES: Technique appraisal of collagen matrix to repair spinal dura following incident...
Helen E. Gruber, Tracy Johnson, Kelly Leslie, Jane A. Ingram et al.
STUDY DESIGN: Work presented here used a small animal model to illustrate the feasibility of autologous disc cell implantation. OBJECTIVES: To develop a small animal model for autologous disc cell implantation. SUMMARY OF THE BACKGROUND DATA: The use of autologous disc cells in the potential treatme...
Dongliang Wang, Sheng‐Dan Jiang, Li‐Yang Dai
STUDY DESIGN: This study attempts to determine the biologic response of the intervertebral disc to static and dynamic compression in vitro. OBJECTIVE: To quantitate and compare the changes of histology, Type I and II collagens, aggrecan, interleukin (IL)-1beta, and tumor necrosis factor (TNF)-alpha ...
Dawn M. Elliott, Joseph J. Sarver
STUDY DESIGN: Measure the mechanical properties of the mouse and rat disc in compression and torsion. OBJECTIVES: Validate mouse and rat disc as a biomechanical model of the human disc by comparing the normalized properties in compression and torsion loading. SUMMARY OF BACKGROUND DATA: Rodents have...
Chan Shik Shim, Sang‐Ho Lee, Ho-Dong Shin, Han Sug Kang et al.
In Brief Study Design. A retrospective study. Objectives. To evaluate and compare clinical and radiologic outcomes of the CHARITÉ and ProDisc. Summary of Background Data. There is no clinical report comparing CHARITÉ and ProDisc. Methods. Among a total of 61 patients who underwent total disc replace...
Casey L. Korecki, Jeffrey J. MacLean, James C. Iatridis
STUDY DESIGN: A bovine intervertebral disc organ culture model was used to study the effect of dynamic compression magnitude on mechanical behavior and measurement of biosynthesis rate, cell viability, and mRNA expression. OBJECTIVE: The objective of this study was to examine the effect of loading m...
Kevin A. Gillespie, James P. Dickey
STUDY DESIGN: Porcine lumbar spine specimens were cyclically loaded in flexion and extension with a pure moment. The resistance to flexion and extension of the individual spinal elements was quantified using a sequential resection procedure. OBJECTIVE: To determine the biomechanical contribution of ...
Caroline N. Demers, John Antoniou, Fackson Mwale
In Brief Study Design. The contents of DNA, proteoglycan, type II collagen, and denatured type II collagen in the bovine coccygeal intervertebral discs were examined in situ in relation to disc level, age, and tissue region. Objective. To determine whether bovine coccygeal discs are a suitable model...
Masahiko Takahata, Manabu Ito, Kuniyoshi Abumi, Yoshihisa Kotani et al.
STUDY DESIGN: A retrospective review. OBJECTIVE: This study examined the clinical outcomes of circumferential spinal cord decompression through a posterior approach for thoracic ossification of posterior longitudinal ligament (OPLL), to determine the efficacy of this procedure and the incidence of c...
Konstantin V. Chernukha, Richard H. Daffner, Donald H. Reigel
STUDY DESIGN: A historic cross-sectional study of lumbar lordosis in 199 healthy individuals aged 1-30 years. OBJECTIVE: To evaluate the magnitude and rate of the development of the normal lumbar lordotic curve with age using two methods of measurement. SUMMARY OF BACKGROUND DATA: There is no agreem...
H. J. M. Barnett, E. H. Botterell, A T Jousse, Megan Wynn-Jones
Journal Article PROGRESSIVE MYELOPATHY AS A SEQUEL TO TRAUMATIC PARAPLEGIA Get access H. J. M. BARNETT, H. J. M. BARNETT Assistant Professor 2Department of Medicine (Neurology) University of Toronto Search for other works by this author on: Oxford Academic PubMed Google Scholar E. H. BOTTERELL, E. H...
Liang Chen, Huilin Yang, Tiansi Tang
STUDY DESIGN: A prospective study of patients who underwent multilevel balloon kyphoplasty at a single institute. OBJECTIVE: To examine and compare the safety and long-term radiographic and clinical effects of unilateral or bilateral balloon kyphoplasty to treat multilevel symptomatic vertebral comp...
Renata Ganko, Prashanth J. Rao, Kevin Phan, Ralph J. Mobbs
STUDY DESIGN: Systematic review and meta-analysis. OBJECTIVE: To review and assess the current evidence from the literature on the potential association between disc infection with the development of symptomatic degenerative disc disease. SUMMARY OF BACKGROUND DATA: The potential relationship betwee...