Marie Ng, Tom Fleming, Margaret S. Robinson, Blake Thomson et al.
Background In 2010, overweight and obesity were estimated to cause 3.4 million deaths, 3.9% of years of life lost, and 3.8% of DALYs globally. The rise in obesity has led to widespread calls for regular monitoring of changes in overweight and obesity prevalence in all populations. Comparative, up-to...
Karen L. Kotloff, James P. Nataro, William C. Blackwelder, Dilruba Nasrin et al.
Background Diarrhoeal diseases cause illness and death among children younger than 5 years in low-income countries. We designed the Global Enteric Multicenter Study (GEMS) to identify the aetiology and population-based burden of paediatric diarrhoeal disease in sub-Saharan Africa and south Asia. Met...
Zulfiqar A Bhutta, Tahmeed Ahmed, Robert E. Black, Simon Cousens et al.
We reviewed interventions that affect maternal and child undernutrition and nutrition-related outcomes. These interventions included promotion of breastfeeding; strategies to promote complementary feeding, with or without provision of food supplements; micronutrient interventions; general supportive...
Susan Walker, Theodore D. Wachs, Sally Grantham‐McGregor, Maureen M. Black et al.
Inequality between and within populations has origins in adverse early experiences. Developmental neuroscience shows how early biological and psychosocial experiences affect brain development. We previously identified inadequate cognitive stimulation, stunting, iodine deficiency, and iron-deficiency...
Michael S. Kramer, Ritsuko Kakuma
BACKGROUND: Although the health benefits of breastfeeding are widely acknowledged, opinions and recommendations are strongly divided on the optimal duration of exclusive breastfeeding. Since 2001, the World Health Organization has recommended exclusive breastfeeding for six months. Much of the recen...
Sathish Subramanian, Sayeeda Huq, Tanya Yatsunenko, Rashidul Haque et al.
Therapeutic food interventions have reduced mortality in children with severe acute malnutrition (SAM), but incomplete restoration of healthy growth remains a major problem. The relationships between the type of nutritional intervention, the gut microbiota, and therapeutic responses are unclear. In ...
Bangladesh Dhaka
James A Platts-Mills, Sudhir Babji, Ladaporn Bodhidatta, Jean Gratz et al.
BACKGROUND: Most studies of the causes of diarrhoea in low-income and middle-income countries have looked at severe disease in people presenting for care, and there are few estimates of pathogen-specific diarrhoea burdens in the community. METHODS: We undertook a birth cohort study with not only int...
David A. Sack, R. Bradley Sack, G. Balakrish Nair, Siddique Ak
Intestinal infection with Vibrio cholerae results in the loss of large volumes of watery stool, leading to severe and rapidly progressing dehydration and shock. Without adequate and appropriate rehydration therapy, severe cholera kills about half of affected individuals. Cholera toxin, a potent stim...
Christopher Troeger, Ibrahim A. Khalil, Puja C Rao, Shujin Cao et al.
Importance: Rotavirus infection is the global leading cause of diarrhea-associated morbidity and mortality among children younger than 5 years. Objectives: To examine the extent of rotavirus infection among children younger than 5 years by country and the number of deaths averted because of the rota...
Stephen P. Luby, Mahbubur Rahman, Benjamin F. Arnold, Leanne Unicomb et al.
BACKGROUND: Diarrhoea and growth faltering in early childhood are associated with subsequent adverse outcomes. We aimed to assess whether water quality, sanitation, and handwashing interventions alone or combined with nutrition interventions reduced diarrhoea or growth faltering. METHODS: The WASH B...
Martin Ravallion, Quentin Wodon
It is often argued that child labour comes at the expense of schooling and so perpetuates poverty for children from poor families. To test this claim we study the effects on children's labour force participation and school enrollments of the pure school-price change induced by a targeted enrollment ...
Mercedes de Onís, Adelheid W. Onyango, Elaine Borghi, Cutberto Garza et al.
OBJECTIVES: To compare growth patterns and estimates of malnutrition based on the World Health Organization (WHO) Child Growth Standards ('the WHO standards') and the National Center for Health Statistics (NCHS)/WHO international growth reference ('the NCHS reference'), and discuss implications for ...
Jason B Harris, Regina C LaRocque, Firdausi Qadri, Edward T Ryan et al.
Cholera is an acute, secretory diarrhoea caused by infection with Vibrio cholerae of the O1 or O139 serogroup. It is endemic in more than 50 countries and also causes large epidemics. Since 1817, seven cholera pandemics have spread from Asia to much of the world. The seventh pandemic began in 1961 a...
Jason Corburn, David Vlahov, Blessing Mberu, Lee W. Riley et al.
The informal settlements of the Global South are the least prepared for the pandemic of COVID-19 since basic needs such as water, toilets, sewers, drainage, waste collection, and secure and adequate housing are already in short supply or non-existent. Further, space constraints, violence, and overcr...