Md. Tanvir Kabir, Mohammad Abu Sufian, Md. Sahab Uddin, Mst. Marium Begum et al.
Alzheimer's disease (AD) is a progressive neurodegenerative disease that causes problems with memory, thinking, and behavior. Currently, there is no drug that can reduce the pathological events of this degenerative disease but symptomatic relief is possible that can abate the disease condition. N-me...
Ashwani Arya, Rubal Chahal, Rekha Rao, Md. Habibur Rahman et al.
Alzheimer’s disease (AD) is a gradually growing irreversible illness of the brain that almost affects every fifth person (aged > 80 years) in the world. World Health Organization (WHO) also revealed that the prevalence of this disease will enhance (upto double) significantly upto 2030. The poor c...
Md. Sahab Uddin, Abdullah Al Mamun, Md. Sarwar Hossain, Farjana Akter et al.
(EEPE) ripe (EEPEr) and EEPE unripe (EEPEu) fruits on cognitive functions, brain antioxidant enzymes, and acetylcholinesterase (AChE) activity in rat. The effects of EEPEr and EEPEu fruits (i.e., 100 and 200 mg/kg b.w.) were examined in Swiss albino male rats for 12 days and its effect on cognitive ...
Afroza Rahman, Md. Anwar Hossen, Mirza Farhana Iqbal Chowdhury, Sadia Bari et al.
Aducanumab is a novel disease-modifying anti-amyloid-beta (Aβ) human monoclonal antibody specifically targeted to the pathophysiology of Alzheimer's disease (AD). It was granted for treating AD in June 2021 by the United States Food and Drug Administration. We systematically analyzed available trial...
Samarpita Banerjee, Uttpal Anand, Suchhanda Ghosh, Durga Ray et al.
From ancient history, complementary and alternative medicines have played a significant role as holistic therapeutic treatments of various human diseases including cancer, diabetes, neurological diseases, and skin problems. One Indian medicinal plant (herb), Bacopa monnieri has been used in many par...
Maroua Jalouli, Md. Ataur Rahman, Partha Biswas, Hasanur Rahman et al.
Polyphenols, naturally occurring phytonutrients found in plant-based foods, have attracted significant attention for their potential therapeutic effects in neurological diseases and neuroinflammation. These compounds possess diverse neuroprotective capabilities, including antioxidant, anti-inflammat...
Md. Sahab Uddin, Md. Tanvir Kabir, Devesh Tewari, Bijo Mathew et al.
Alzheimer's disease (AD) is a progressive, chronic and severe neurodegenerative disorder linked with cognitive and memory impairment that eventually lead to death. There are several processes which can cause AD, including mitochondrial dysfunction-mediated oxidative stress (OS), intracellular buildu...
Md. Hasibur Rahman, Mohammad Omar Faruq, Talha Bin Abdul Hai, Wahidur Rahman et al.
The recent statistics on Agriculture identically remarks the massive contributions of mushroom farming in the Global market. Thus, the popularity of mushroom farming and cultivation is increasing day after day. Weather monitoring and management is a significant feature for mushroom growth, especiall...
Rezaul Islam, Aubhishek Zaman, Iffat Jahan, Rajib Chakravorty et al.
UNLABELLED: Acetylcholine-esterase (AchE) inhibitors are one of the most potent drug molecules against Alzheimer's disease (AD). But, patients treated with current AchE inhibitors often experience severe side effects. Quercetin is a plant flavonoid compound which can act as AchE inhibitor and it may...
Rashid Taqui, Mithila Debnath, Safin Ahmed, Ajit Ghosh
Alzheimer's disease (AD) is a neurodegenerative disease caused by the formation of amyloid-beta (Aβ) plaques and neurofibrillary tangles. Acetylcholinesterase (AChE), a serine hydrolase, is the crucial enzyme in the hydrolysis of one of the most extensively known neurotransmitters acetylcholine (ACh...
Md. Sahab Uddin, Abdullah Al Mamun, Md. Tanvir Kabir, Ghulam Md Ashraf et al.
Alzheimer's disease (AD) is one of the most common forms of dementia among elder people, which is a progressive neurodegenerative disease that results from a chronic loss of cognitive activities. It has been observed that AD is multifactorial, hence diverse pharmacological targets that could be foll...
Fahadul Islam, Jannatul Fardous Khadija, Md. Harun-Or-Rashid, Md. Saidur Rahaman et al.
) AD aggregation, neuroinflammation, and several other pathways. AD is still the most prevalent form of dementia and affects many individuals across the globe. The exact cause of the disorder is obscure. There are yet no effective medications for halting, preventing, or curing AD's progress. Plenty ...
Md Mahmudul Hasan, Zidan Khan, Mohammed Salahuddin Chowdhury, Md. Arif Khan et al.
Progression in computational research has made it possible for the in silico methods to offer epochal benefits to both regulatory needs and the pharmaceutical industry to assess the safety profile. Myriad amounts of flavonoids are present in the human diet. They showed potential therapeutic effects ...
A.S.M. Ali Reza, Mohammad Shahadat Hossain, Sharmin Akhter, Md Rezanur Rahman et al.
BACKGROUND: Alzheimer's disease (AD), one of the major causes of dementia, is an overwhelming neurodegenerative disease that particularly affects the brain, leading to memory loss and impairment of language and judgment capacity. The aim of the present study was to investigate the antioxidant and an...
Dew Biswas, Sujata Mandal, Suchismita Chatterjee Saha, Champa Keeya Tudu et al.
The well-known medicinal plant Centella asiatica (L.) Urban is an Ayurvedic and traditional Chinese medicine used in the treatment of different health problems and as an edible vegetable in a regular diet. Ease of availability in the wide range of environmental conditions plus low-cost cultivation p...