Chuangshi Wang, Shrikant I. Bangdiwala, Sumathy Rangarajan, Scott A. Lear et al.
AIMS: To investigate the association of estimated total daily sleep duration and daytime nap duration with deaths and major cardiovascular events. METHODS AND RESULTS: We estimated the durations of total daily sleep and daytime naps based on the amount of time in bed and self-reported napping time a...
Muhammad Ahsan Altaf, Rabia Shahid, Ming‐Xun Ren, Safina Naz et al.
Tomato is an important vegetable that is highly sensitive to drought (DR) stress which impairs the development of tomato seedlings. Recently, melatonin (ME) has emerged as a nontoxic, regulatory biomolecule that regulates plant growth and enhances the DR tolerance mechanism in plants. The present st...
Mohammad Shah Jahan, Sheng Shu, Yu Wang, Zheng Chen et al.
BACKGROUND: Melatonin is a pleiotropic signaling molecule that plays multifarious roles in plants stress tolerance. The polyamine (PAs) metabolic pathway has been suggested to eliminate the effects of environmental stresses. However, the underlying mechanism of how melatonin and PAs function togethe...
Biswojit Debnath, Waqar Islam, Min Li, Yueting Sun et al.
Melatonin is a multifunctional signaling molecule, ubiquitously distributed in different parts of plants and responsible for stimulating several physiological responses to adverse environmental conditions. In the current review, we showed that the biosynthesis of melatonin occurred in plants by them...
Md. Sahab Uddin, Devesh Tewari, Abdullah Al Mamun, Md. Tanvir Kabir et al.
Alzheimer's disease (AD) is a devastating and irreversible cognitive impairment and the most common type of dementia. Along with progressive cognitive impairment, dysfunction of the circadian rhythms also play a pivotal role in the progression of AD. A mutual relationship among circadian rhythms, sl...
Muzahidul I. Anik, Niaz Mahmud, Abdullah Al Masud, Md Ishak Khan et al.
Research on the role of reactive oxygen species (ROS) in the aging process has advanced significantly over the last two decades. In light of recent findings, ROS takes part in the aging process of cells along with contributing to various physiological signaling pathways. Antioxidants being cells' na...
Md. Farhad Hossain, Md. Sahab Uddin, G. M. Sala Uddin, Dewan Md. Sumsuzzman et al.
Melatonin, a pineal gland synthesized neurohormone is known as a multifunctioning pleiotropic agent which has a wide range of neuroprotective role in manifold age-related neurodegenerative disorders especially Alzheimer's diseases (AD). AD is a devastating neurodegenerative disorder and common form ...
Santosh Kumar Bose, Prianka Howlader
Melatonin (N-acetyl-5-methoxytryptamine) is a multifunctional nontoxic signaling molecule, universally distributed in different plant organs and accountable for invigorating numerous physiological mechanisms against various adverse environmental factors. In the current review, we revealed that the b...
Abdelaleim Ismail ElSayed, Mohamed Suhail Rafudeen, Ayman M. Gomaa, Mirza Hasanuzzaman
Melatonin (MT) has been reported to regulate certain plant physiological processes and promote tolerance to different environmental stresses such as salinity. Green bean (Phaseolus vulgaris L. cv. Royal Nel) seedlings were exposed to 200 mM NaCl with or without pre-treatment with 150 μM MT. Salt str...
Yinxia Li, Shunhui Yu, Qiuli Wu, Meng Tang et al.
In this study, we investigated genetic mechanisms of neurotransmitters in regulating the formation of adverse effects on locomotion behavior in Al2O3 nanoparticles (NPs)-exposed Caenorhabditis elegans. Al2O3-NPs exposure caused the decrease of locomotion behavior with head thrash and body bend as en...
Md. Ismail Hosen, Mahdi Sheikh, Maria I. Zvereva, Ghislaine Scélo et al.
BACKGROUND: Detecting pre-clinical bladder cancer (BC) using urinary biomarkers may provide a valuable opportunity for screening and management. Telomerase reverse transcriptase (TERT) promoter mutations detectable in urine have emerged as promising BC biomarkers. METHODS: We performed a nested case...
Md. Abdul Hannan, Md. Ataur Rahman, Md Saidur Rahman, Abdullah Al Mamun Sohag et al.
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the causative pathogen of deadly Coronavirus disease-19 (COVID-19) pandemic, which emerged as a major threat to public health across the world. Although there is no clear gender or socioeconomic discrimination in the incidence of COVID-...
Tanvir Ahmed, Sai Krupa Das, Julie K. Golden, Edward Saltzman et al.
Calorie restriction (CR) enhances immune response and prolongs life span in animals. However, information on the applicability of these results to humans is limited. T-cell function declines with age. We examined effects of CR on T-cell function in humans. Forty-six overweight, nonobese participants...
Stella J. M. Druiven, Johanna Hovenkamp-Hermelink, Stefan E. Knapen, Jeanine Kamphuis et al.
BACKGROUND: Chronotype is an individual's preferred timing of sleep and activity, and is often referred to as a later chronotype (or evening-type) or an earlier chronotype (or morning-type). Having an evening chronotype is associated with more severe depressive and anxiety symptoms. Based on these f...
Anastasiia D. Shkodina, Shing Cheng Tan, Mohammad Mehedi Hasan, Mai Abdelgawad et al.
Parkinson's disease (PD) is a common motor disorder that has become increasingly prevalent in the ageing population. Recent works have suggested that circadian rhythms disruption is a common event in PD patients. Clock genes regulate the circadian rhythm of biological processes in eukaryotic organis...