Tahmeed Ahmed, Mohammad Ali, Mohammad Mofiz Ullah, Ireen A Choudhury et al.
Background Severely malnourished children have high mortality rates. Death commonly occurs during the first 48 h after hospital admission, and has been attributed to faulty case-management. We developed a standardised protocol for acute-phase treatment of children with severe malnutrition and diarrh...
W. Abdullah Brooks, Mohammad Yunus, Mathuram Santosham, MA Wahed et al.
Background Pneumonia is a leading cause of morbidity and mortality in young children. Early reversal of severity signs--chest indrawing, hypoxia, and tachypnoea--improves outcome. We postulated that zinc, an acute phase reactant, would shorten duration of severe pneumonia and time in hospital. Metho...
APASL ACLF Working Party, Ashok Choudhury, Ankur Jindal, Rakhi Maiwall et al.
Background and aims Acute-on-chronic liver failure (ACLF) is a progressive disease associated with rapid clinical worsening and high mortality. Early prediction of mortality and intervention can improve patient outcomes. We aimed to develop a dynamic prognostic model and compare it with the existing...
Lindsey Lenters, Kerri Wazny, Patrick Webb, Tahmeed Ahmed et al.
BACKGROUND: Globally, moderate acute malnutrition (MAM) and severe acute malnutrition (SAM) affect approximately 52 million children under five. This systematic review evaluates the effectiveness of interventions for SAM including the World Health Organization (WHO) protocol for inpatient management...
Roy Sk, R.H. Behrens, Rukhsana Haider, S. M. Akramuzzaman et al.
Zinc has been shown to enhance intestinal mucosal repair in patients suffering from acrodermatitis enteropathica; but the impact on mucosal integrity during acute (AD) or persistent (PD) diarrhoea is unknown. One hundred eleven children with AD and 190 with PD aged between 3 and 24 months received, ...
DavidA. Sack, A Eusof, MichaelH. Merson, RobertE. Black et al.
Of 57 male children, aged 5 months to 2 1/2 years with rotavirus diarrhoea, 28 were given oral therapy with sucrose electrolyte solution and 29 were given glucose electrolyte solution in a randomised double-blind trial. All were rehydrated and remained so on oral therapy alone. These patients were c...
Emma Osland, M. Belal Hossain, Shahjahan Khan, Muhammed Ashraf Memon
BACKGROUND: Pharmaconutrition has previously been reported in elective surgery to reduce postoperative infective complications and duration of hospital length of stay. OBJECTIVE: To update previously published meta-analyses and elucidate potential benefits of providing arginine-dominant pharmaconutr...
Thomas Butler, Joseph A. Knight, S. Nath, Peter Speelman et al.
In Bangladesh, clinical records of 323 patients with typhoid fever were reviewed to study the incidence, fatality, and optimal therapy of the complication of intestinal perforation. Fifteen patients (4.6%) developed intestinal perforation. Case-fatality rates were six of nine patients treated medica...
Mohammod Jobayer Chisti, Stephen M. Graham, Trevor Duke, Tahmeed Ahmed et al.
BACKGROUND: Post-discharge mortality among children with severe illness in resource-limited settings is under-recognized and there are limited data. We evaluated post-discharge mortality in a recently reported cohort of children with severe malnutrition and pneumonia, and identified characteristics ...
Gary L. Darmstadt, Samir K. Saha
Topical application of natural oils is practised routinely in many countries and may either improve skin barrier function and health or have detrimental cutaneous and systemic effects, depending on the composition of the oil. Little literature on the epidemiology, practice, and perceptions of tradit...
Ryan T. Hurt, Stephen A. McClave, Robert G. Martindale, Juan B. Ochoa Gautier et al.
The International Protein Summit in 2016 brought experts in clinical nutrition and protein metabolism together from around the globe to determine the impact of high-dose protein administration on clinical outcomes and address barriers to its delivery in the critically ill patient. It has been sugges...
Stephen A. McClave, Mohamed Saad, Mark E. Esterle, Mary E. Anderson et al.
INTRODUCTION: Critically ill patients placed on enteral nutrition (EN) are usually underfed. A volume-based feeding (VBF) protocol designed to adjust the infusion rate to make up for interruptions in delivery should provide a greater volume of EN than the more common fixed hourly rate-based feeding ...
Farzad Saberi, Daren K. Heyland, Miu Lam, D. RAPSON et al.
BACKGROUND: The primary objective of this study was to measure the prevalence, incidence, and resolution of insulin resistance (IR) in critically ill patients. A secondary objective was to explore the relationship between IR and inflammatory cytokines, coagulation abnormalities, and clinical outcome...
Robert H. Gilman, Raija Partanen, Kenneth H. Brown, William M. Spira et al.
To assess the effect of malnutrition on gastric acidity and gastric bacterial colonization, we studied 35 severely malnourished Bangladeshi children before (0 wk) and after (3 wk) they received nutritional rehabilitation for 3 wk. These results were compared with those obtained from a similarly exam...
Md. Abu Musa, Mamun Kabir, Md Iqbal Hossain, Emtiaz Ahmed et al.
Urinary excretion of two orally-administered non-metabolizable sugars, lactulose and mannitol, is a valuable marker for evaluating intestinal permeability. Usually this test involves a time consuming procedure of about 5 hour's urine collection, which makes the test incompatible to some extent. As t...