John B. Holcomb, Neil R. McMullin, Lisa Pearse, Jim Caruso et al.
In Brief Background: Effective combat trauma management strategies depend upon an understanding of the epidemiology of death on the battlefield. Methods: A panel of military medical experts reviewed photographs and autopsy and treatment records for all Special Operations Forces (SOF) who died betwee...
Coleman Rotstein, Gerald A. Evans, Abraham Born, Ronald F. Grossman et al.
Hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) are important causes of morbidity and mortality, with mortality rates approaching 62%. HAP and VAP are the second most common cause of nosocomial infection overall, but are the most common cause documented in the intensive c...
Daren K. Heyland, Allan Garland, Sean M. Bagshaw, Deborah Cook et al.
Purpose Increasingly, very old patients are admitted to Intensive Care Units (ICUs). The objective of this study was to describe 12-month outcomes of these patients and determine which characteristics are associated with a return to baseline physical function 1 year later. Methods In this prospectiv...
Md Maniruzzaman, Mir Atiqur Rahaman
The article is reprinted after 'Lancet 2010; 376: 23-32' by the above collaborators with written permission from Lancet Authority.Background: Tranexamic acid can reduce bleeding in patients undergoing elective surgery. We assessed the effects of early administration of a short course of tranexamic a...
Mohammod Jobayer Chisti, Mohammed Abdus Salam, Jonathan H. Smith, Tahmeed Ahmed et al.
Background In developing countries, mortality in children with very severe pneumonia is high, even with the provision of appropriate antibiotics, standard oxygen therapy, and other supportive care. We assessed whether oxygen therapy delivered by bubble continuous positive airway pressure (CPAP) impr...
John Muscedere, Tasnim Sinuff, Daren K. Heyland, Peter Dodek et al.
Background Ventilator-associated conditions (VACs) and infection-related ventilator-associated complications (iVACs) are the Centers for Disease Control and Prevention's new surveillance paradigms for patients who are mechanically ventilated. Little is known regarding the clinical impact and prevent...
Aaron Epstein, Robert B. Lim, Jay A. Johannigman, Charles J. Fox et al.
In the past 20 years of the Global War on Terror, the US has seen substantial improvements in its system of medical delivery in combat. However, throughout that conflict, enemy forces did not have parity with the weaponry, capability, or personnel of the US and allied forces. War against countries l...
Md Asiful Islam, Shoumik Kundu, Sayeda Sadia Alam, Tareq Hossan et al.
BACKGROUND: Coronavirus disease 2019 (COVID-19), a pandemic disease caused by the severe acute respiratory syndrome coronavirus 2 started to spread globally since December 2019 from Wuhan, China. Fever has been observed as one of the most common clinical manifestations, although the prevalence and c...
Waleed Alhazzani, Gordon Guyatt, Mohammed Alshahrani, Adam M. Deane et al.
INTRODUCTION: A decreased frequency of upper gastrointestinal bleeding and a possible association of proton pump inhibitor use with Clostridium difficile and ventilator-associated pneumonia have raised concerns recently. The Reevaluating the Inhibition of Stress Erosions Pilot Trial determined the f...
Ankan Ghosh Dastider, Farhan Sadik, Shaikh Anowarul Fattah
The COVID-19 pandemic has become one of the biggest threats to the global healthcare system, creating an unprecedented condition worldwide. The necessity of rapid diagnosis calls for alternative methods to predict the condition of the patient, for which disease severity estimation on the basis of Lu...
Azizur Rahman, Md. Moyazzem Hossain
BACKGROUND: Although efforts have been made by the international community to improve childhood health, risk factors linked with the healthiness of preschool-age children in low and middle-income countries (LMICs) are very diverse. Therefore, this paper examines the prevalence and determinants of fe...
Lovely Barai, Kaniz Fatema, Jalaluddin Ashraful Haq, Mohammad Omar Faruq et al.
Critically ill patients admitted in intensive care units (ICU) are always at a higher risk of developing infections with various antibiotic resistant organisms. The objective of this study was to know the antibiotic resistance pattern of the common isolates from blood, urine, respiratory secretions ...
Barbara M.Q. Weaver, R.V. Walley
SUMMARY Eleven out of 12 horses were underventilating while breathing spontaneously during halothane anaesthesia with high arterial carbon dioxide tensions. In addition, large alveolar to arterial oxygen tension gradients were found to be present. Mechanically, controlled ventilation with an intermi...
David Astapenko, Jan Beneš, Jiří Pouska, Christine Lehmann et al.
The endothelial glycocalyx (EG) is the thin sugar-based lining on the apical surface of endothelial cells. It has been linked to the physiological functioning of the microcirculation and has been found to be damaged in critical illness and after acute care surgery. This review aims to describe the r...
Gabriela SS Chaves, Guilherme Fregonezi, Fernando AL Dias, Cibele TD Ribeiro et al.
BACKGROUND: Pneumonia is a lung infection that causes more deaths in children aged under five years than any other single cause. Chest physiotherapy is widely used as adjuvant treatment for pneumonia. Physiotherapy is thought to help remove inflammatory exudates, tracheobronchial secretions, and air...