Simon Wanninger, Volker Lorenz, Md Abdus Subhan, Frank T. Edelmann
This Tutorial Review presents an overview on the synthesis, characterization and applications of metal complexes containing curcumin (=1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) and its derivatives as ligands. Innovative synthetic strategies leading to soluble and crystallizable me...
Hitesh Chopra, Protity Shuvra Dey, Debashrita Das, Tanima Bhattacharya et al.
is curcumin and has gained importance in various treatments of various disorders such as antibacterial, antiprotozoal, cancer, obesity, diabetics and wound healing applications. Several techniques had been exploited as reported by researchers for increasing the therapeutic potential and its pharmaco...
E. M. Tanvir, Md. Sakib Hossen, Md. Fuad Hossain, Rizwana Afroz et al.
We investigated the aqueous and ethanolic extracts of different forms (local names: mura and chora ) of turmeric (Curcuma longa) from the Khulna and Chittagong divisions of Bangladesh for their antioxidant properties and polyphenol, flavonoid, tannin, and ascorbic acid contents. The antioxidant acti...
Md. Tanvir Kabir, Md. Habibur Rahman, Rokeya Akter, Tapan Behl et al.
Cancer is a major burden of disease globally. Each year, tens of millions of people are diagnosed with cancer worldwide, and more than half of the patients eventually die from it. Significant advances have been noticed in cancer treatment, but the mortality and incidence rates of cancers are still h...
Qi Zhang, Cong Zhang, Jing Ge, Mei‐Wei Lv et al.
Cadmium (Cd) is a toxic pollutant with high nephrotoxicity in the agricultural environment. Resveratrol has been found to have a renoprotective effect but the underlying mechanisms of this have not yet been fully elucidated. The aim of this study is to illustrate the antagonism of resveratrol agains...
Priti Tagde, Pooja Tagde, Fahadul Islam, Sandeep Tagde et al.
Curcumin is the primary polyphenol in turmeric's curcuminoid class. It has a wide range of therapeutic applications, such as anti-inflammatory, antioxidant, antidiabetic, hepatoprotective, antibacterial, and anticancer effects against various cancers, but has poor solubility and low bioavailability....
Safiul Islam, Md Mir Shakib Ahmed, Mohammad Aminul Islam, Nayem Hossain et al.
Nanoparticles have transformed contemporary medicine by improving bioavailability, targeting, and drug release mechanisms. Traditional drug delivery methods typically exhibit minimal therapeutic efficacy due to rapid elimination, inadequate solubility, and systemic toxicity. The distinctive physicoc...
H. M. Arif Ullah, Sayera Zaman, Fatematuj Juhara, Lucky Akter et al.
BACKGROUND: The present study was aimed to investigate the antinociceptive and anti-inflammatory activity of the Curcuma zedoaria (family Zingiberaceae) ethanolic rhizome extract in laboratory using both in vitro and in vivo methods so as to justify its traditional use in the above mentioned patholo...
Md. Rezaul Islam, Abdur Rauf, Shopnil Akash, Sadiya Islam Trisha et al.
The curry powder spices turmeric (Curcuma longa L.), which contains curcumin (diferuloylmethane), an orange-yellow chemical. Polyphenols are the most commonly used sources of curcumin. It combats oxidative stress and inflammation in diseases, such as hyperlipidemia, metabolic syndrome, arthritis, an...
Jesmin Akter, Md. Amzad Hossain, Kensaku Takara, Md. Zahorul Islam et al.
There are >80 species of turmeric (Curcuma spp.) and some species have multiple varieties, for example, Curcuma longa (C. longa) has 70 varieties. They could be different in their chemical properties and biological activities. Therefore, we compared antioxidant activity, total phenolic and flavonoid...
Md. Sahab Uddin, Abdullah Al Mamun, Md. Tanvir Kabir, Jamil Ahmad et al.
Neurodegenerative diseases (NDs) are characterized by disorders with progressive deterioration of the structure and/or function of neurons. Genetic mutations can lead to many NDs. Nevertheless, neurodegeneration can also take place due to several biological processes. The pathogenesis of several NDs...
Rejina Afrin, Somasundaram Arumugam, Md. Azizur Rahman, Mir Imam Ibne Wahed et al.
Curcumin, a phenolic compound, has a wide spectrum of therapeutic effects such as antitumor, anti-inflammatory, anti-cancer and so on. The study aimed to investigate the underlying mechanisms of curcumin to protect liver damage and progression of non-alcoholic steatohepatitis (NASH) in a novel NASH-...
Raushanara Akter, Afrina Afrose, Md. Rashidur Rahman, Rakhi Chowdhury et al.
Natural products have long been used as drugs to treat a wide array of human diseases. The lead compounds discovered from natural sources are used as novel templates for developing more potent and safer drugs. Natural products produce biological activity by binding with biological macromolecules, si...
Arjun Thapa, Eun‐Rhan Woo, Eva Y., Md Golam Sharoar et al.
Polymerization of monomeric amyloid-β peptides (Aβ) into soluble oligomers and insoluble fibrils is one of the major pathways triggering the pathogenesis of Alzheimer's disease (AD). Using small molecules to prevent the polymerization of Aβ peptides can, therefore, be an effective therapeutic strate...
Maroua Jalouli, Md. Ataur Rahman, Partha Biswas, Hasanur Rahman et al.
Polyphenols, naturally occurring phytonutrients found in plant-based foods, have attracted significant attention for their potential therapeutic effects in neurological diseases and neuroinflammation. These compounds possess diverse neuroprotective capabilities, including antioxidant, anti-inflammat...