Jeremiah Chakaya, Mishal Khan, Francine Ntoumi, Eleni Aklillu et al.
The October 2020 Global TB report reviews TB control strategies and United Nations (UN) targets set in the political declaration at the September 2018 UN General Assembly high-level meeting on TB held in New York. Progress in TB care and prevention has been very slow. In 2019, TB remained the most c...
Karine Brudey, Jeffrey Driscoll, Leen Rigouts, Wolfgang M. Prodinger et al.
BACKGROUND: The Direct Repeat locus of the Mycobacterium tuberculosis complex (MTC) is a member of the CRISPR (Clustered regularly interspaced short palindromic repeats) sequences family. Spoligotyping is the widely used PCR-based reverse-hybridization blotting technique that assays the genetic dive...
Rashidul Haque, Christopher D. Huston, Molly A. Hughes, Eric R. Houpt et al.
Infection with Entamoeba histolytica can lead to amebic colitis and to complications including liver abscess. This review summarizes recent research on the pathogenesis and treatment of infection and the prospects for the development of a vaccine. A mucosal IgA response can produce partial, protecti...
Stephen M. Graham, Tahmeed Ahmed, Farhana Amanullah, Renee Browning et al.
There is a critical need for improved diagnosis of tuberculosis in children, particularly in young children with intrathoracic disease as this represents the most common type of tuberculosis in children and the greatest diagnostic challenge. There is also a need for standardized clinical case defini...
Rashidul Haque, Ibne Karim M. Ali, Selim Akther, William A. Petri
The diagnosis of amebiasis by microscopic identification of the parasite in stool is insensitive and unable to distinguish the invasive parasite Entamoeba histolytica from the commensal parasite E. dispar. In this study, we have tested a PCR technique for the detection of E. histolytica and compared...
Rashidul Haque, Nasir Uddin Mollah, Ibne Karim M. Ali, Khorshed Alam et al.
A noninvasive diagnostic test for amebic liver abscess is needed, because amebic and bacterial abscesses appear identical on ultrasound or computer tomography and because it is rarely possible to identify Entamoeba histolytica in stool specimens from patients with amebic liver abscess. Here we repor...
Jean Jacques Noubiap, Jobert Richie Nansseu, Ulrich Flore Nyaga, Jan René Nkeck et al.
BackgroundAlthough diabetes and poor glycaemic control significantly increase the risk of tuberculosis and adversely affect tuberculosis treatment outcomes, the global burden of diabetes in the context of tuberculosis remains unknown. We did a systematic review and meta-analysis to estimate the prev...
Ibne Karin M. Ali, Mohammad Bakhtiar Hossain, Shantanu Roy, Patrick F. Ayeh‐Kumi et al.
Entamoeba moshkovskii cysts are morphologically indistinguishable from those of the disease-causing species E. histolytica and the nonpathogenic E. dispar. Although sporadic cases of human infection with E. moshkovskii have been reported, the organism is considered primarily a free-living amoeba. No...
Rashidul Haque, Ibnekarim M. Ali, R. Bradley Sack, Barry M. Farr et al.
Amebiasis is the third leading parasitic cause of death worldwide, and it is not known whether immunity is acquired from a previous infection. An investigation was done to determine whether protection from intestinal infection correlated with mucosal or systemic antibody responses to the Entamoeba h...
Rashidul Haque, Laurie M. Neville, P Hahn, William A. Petri
Humans are infected by two morphologically identical species of Entamoeba: Entamoeba histolytica causes amebic colitis and liver abscess, and Entamoeba dispar is noninvasive. Several weeks of culture and isoenzyme (zymodeme) analysis are required to differentiate E. histolytica from E. dispar. Here ...
Rashidul Haque, Dinesh Mondal, Priya Duggal, Mamun Kabir et al.
The contribution of amebiasis to the burden of diarrheal disease in children and the degree to which immunity is acquired from natural infection were assessed in a 4-year prospective observational study of 289 preschool children in an urban slum in Dhaka, Bangladesh. Entamoeba histolytica infection ...
Jacob Creswell, Andrew James Codlin, Emmanuel André, Mark A. Micek et al.
BACKGROUND: The Xpert MTB/RIF assay has garnered significant interest as a sensitive and rapid diagnostic tool to improve detection of sensitive and drug resistant tuberculosis. However, most existing literature has described the performance of MTB/RIF testing only in study conditions; little inform...
Rashidul Haque, Shantanu Roy, Abdullah Siddique, Utpal K. Mondal et al.
Entamoeba histolytica, Giardia intestinalis, and Cryptosporidium spp. are not only three of the most important and common diarrhea-causing parasitic protozoa, but they often have similar clinical presentations. Microscopic diagnosis of these parasites is neither sensitive nor specific. Recently, mor...
Matteo Zignol, Andrea Maurizio Cabibbe, Anna Dean, Philippe Glaziou et al.
BACKGROUND: In many countries, regular monitoring of the emergence of resistance to anti-tuberculosis drugs is hampered by the limitations of phenotypic testing for drug susceptibility. We therefore evaluated the use of genetic sequencing for surveillance of drug resistance in tuberculosis. METHODS:...
Rashidul Haque, Abu Syed Golam Faruque, P Hahn, David M. Lyerly et al.
The prevalence of infection by the invasive parasite Entamoeba histolytica and the noninvasive parasite Entamoeba dispar was determined in 2000 children in Bangladesh. Antigen detection identified more cases of E. histolytica-E. dispar infection than did culture or microscopy. Microscopic identifica...