J. M. A. Hannan, Liaquat Ali, Begum Rokeya, J. Khaleque et al.
Trigonella foenum-graecum (fenugreek) seeds have been documented as a traditional plant treatment for diabetes. In the present study, the antidiabetic properties of a soluble dietary fibre (SDF) fraction of T. foenum-graecum were evaluated. Administration of SDF fraction (0 x 5 g/kg body weight) to ...
David J.A. Jenkins, Mahshid Dehghan, Andrew Mente, Shrikant I. Bangdiwala et al.
BACKGROUND: Most data regarding the association between the glycemic index and cardiovascular disease come from high-income Western populations, with little information from non-Western countries with low or middle incomes. To fill this gap, data are needed from a large, geographically diverse popul...
Biazid Alam Shibib, Laazina Khan, R Rahman
Coccinia indica leaves were extracted with 60% ethanol, solvents were evaporated and the residue was suspended in water. This suspension was administered orally at a dose of 200 mg/kg body wt. after 18 h of fasting to normal fed and streptozotocin-induced male diabetic rats (180-250 g). After 90 min...
Md. Mominur Rahman, Puja Sutro Dhar, Sumaia, Fazilatunnesa Anika et al.
Diabetes mellitus (DM) is a metabolic syndrome. Diabetes has become more common in recent years. Chemically generated drugs are used to lessen the effects of DM and its following repercussions due to unpleasant side effects such as weight gain, gastrointestinal issues, and heart failure. On the othe...
Md Mahdi Hasan‐Olive, Knut H. Lauritzen, Mohammad Ali, Lene Juel Rasmussen et al.
A ketogenic diet (KD; high-fat, low-carbohydrate) can benefit refractory epilepsy, but underlying mechanisms are unknown. We used mice inducibly expressing a mutated form of the mitochondrial DNA repair enzyme UNG1 (mutUNG1) to cause progressive mitochondrial dysfunction selectively in forebrain neu...
Devajit Mohajan, Haradhan Kumar Mohajan
At present rising of obesity becomes a principal public global health and economic concern. In 1997, the World Health Organization (WHO) has declared the obesity as global epidemic. About one-third of the world population is now suffering from overweight or obesity. It is estimated that some disease...
Prawej Ansari, Samara T. Choudhury, Véronique Seidel, Akib Bin Rahman et al.
Diabetes Mellitus (DM) is a metabolic disorder that is spreading alarmingly around the globe. Type-2 DM (T2DM) is characterized by low-grade inflammation and insulin resistance and is closely linked to obesity. T2DM is mainly controlled by lifestyle/dietary changes and oral antidiabetic drugs but re...
J. M. A. Hannan, Begum Rokeya, Omar Faruque, Nilufar Nahar et al.
The soluble dietary fibre (SDF) fraction of Trigonella foenum graecum (Tf-sdf) has previously been shown to reduce postprandial elevation in blood glucose level of Type 2 model diabetic rats by delaying the digestion of sucrose. The Tf-sdf has now been investigated for its chronic effect on serum fr...
Ewa Pańkowska, Marlena Błazik, Lidia Groele
BACKGROUND: Our study examines the hypothesis that in addition to sugar starch-type diet, a fat-protein meal elevates postprandial glycemia as well, and it should be included in calculated prandial insulin dose accordingly. The goal was to determine the impact of the inclusion of fat-protein nutrien...
G. A. Hitman, Nasima Mannan, Michael McDermott, E Aganna et al.
Mohammed Eslam, Jian‐Gao Fan, Ming‐Lung Yu, Vincent Wai‐Sun Wong et al.
Metabolic dysfunction-associated fatty liver disease (MAFLD) affects over one-fourth of the global adult population and is the leading cause of liver disease worldwide. To address this, the Asian Pacific Association for the Study of the Liver (APASL) has created clinical practice guidelines focused ...
Md Ashraful Alam, Riaz Uddin, Nusrat Subhan, Mahbubur Rahman et al.
Diabetes, obesity, and metabolic syndrome are becoming epidemic both in developed and developing countries in recent years. Complementary and alternative medicines have been used since ancient era for the treatment of diabetes and cardiovascular diseases. Bitter melon is widely used as vegetables in...
Abu Sadat Md. Sayem, Aditya Arya, Hamed Karimian, Narendiran Krishnasamy et al.
Diabetes is associated with obesity, generally accompanied by a chronic state of oxidative stress and redox imbalances which are implicated in the progression of micro- and macro-complications like heart disease, stroke, dementia, cancer, kidney failure and blindness. All these complications rise pr...
Shahinul Alam, Golam Mustafa, Mahabubul Alam, Nooruddin Ahmad
Although insulin resistance (IR) is strongly associated with nonalcoholic fatty liver disease (NAFLD), the association of IR and NAFLD is not universal and correlation between IR and severity of NAFLD is still controversial. In this review, we summarize recent evidence that partially dissociates ins...
Md Tangigul Haque, Sadaqur Rahman, Shiful Islam, Noyan Hossain Molla et al.
BACKGROUND: In epidemiological studies, serum uric acid (SUA) has been shown to be associated with hypertension and cardiovascular disorders. However, limited studies have evaluated the relationship between SUA and glucose levels in healthy and diabetic individuals and their observed findings are in...
Yi Zhao, De-Xing Ma, Hongguang Wang, Muzi Li et al.
Di(2-ethylhexyl) phthalate (DEHP) is a widespread pollutant that badly affects animals and human health. Lycopene (LYC) has been used as a dietary supplement that has effective antioxidant and antiobesity functions. The present goal was to understand the molecular mechanisms of LYC preventing DEHP-i...
Jolanta B. Pucilowska, Michelle Davenport, I Kabir, David R. Clemmons et al.
Nutrient deficiency causes growth failure and decreases serum insulin-like growth factor-I (IGF-I) concentrations. Because IGFBPs modulate the concentrations and availability of IGFs in serum, IGF-binding proteins (IGFBPs) were measured along with IGF-I and IGF-II before and after 21 days of refeedi...
A Mowl, Mohammad Alauddin, Md. Atiar Rahman, K. Ahmed
The effects of ethanol extract of Trigonella foenum-graecum (Fenugreek) seeds on the blood glucose levels in alloxan-induced diabetic rats at different doses (2g/kg, 1g/kg, 0.5g/kg and 0.1g/kg) were studied. The hypoglycemic effect of extract was compared with that of the standard antidiabetic drug ...
Md. Asrafuzzaman, Yingnan Cao, Rizwana Afroz, Danielle Kamato et al.
Type 2 diabetes mellitus is a complex and heterogeneous disorder which in its most common manifestation arises from insulin resistance and later insulin insufficiency. Type 2 diabetes is characterised by impaired insulin sensitivity and diagnosed as hyperglycaemia. Because of its cardiovascular cons...
Munmun Shabnam Bipasha, Shatabdi Goon
Consumption of takeaway and fast food by young adolescents is no longer confined to the developed countries; it has spread to the developing countries as well. The culture of fast food consumption has replaced the traditional meal among university students and is a great public health concern. Exces...