Alan Kim Johnson, Paul M. Gross
Circumventricular organs (CVOs), small structures bordering the ventricular spaces in the midline of the brain, have common morphological and endocrine-like characteristics that distinguish them from the rest of the nervous system. Among their unique features are cellular contacts with two fluid pha...
Mohammad Shah Jahan, Sheng Shu, Yu Wang, Zheng Chen et al.
BACKGROUND: Melatonin is a pleiotropic signaling molecule that plays multifarious roles in plants stress tolerance. The polyamine (PAs) metabolic pathway has been suggested to eliminate the effects of environmental stresses. However, the underlying mechanism of how melatonin and PAs function togethe...
Biswojit Debnath, Waqar Islam, Min Li, Yueting Sun et al.
Melatonin is a multifunctional signaling molecule, ubiquitously distributed in different parts of plants and responsible for stimulating several physiological responses to adverse environmental conditions. In the current review, we showed that the biosynthesis of melatonin occurred in plants by them...
Md. Sahab Uddin, Devesh Tewari, Abdullah Al Mamun, Md. Tanvir Kabir et al.
Alzheimer's disease (AD) is a devastating and irreversible cognitive impairment and the most common type of dementia. Along with progressive cognitive impairment, dysfunction of the circadian rhythms also play a pivotal role in the progression of AD. A mutual relationship among circadian rhythms, sl...
Md. Farhad Hossain, Md. Sahab Uddin, G. M. Sala Uddin, Dewan Md. Sumsuzzman et al.
Melatonin, a pineal gland synthesized neurohormone is known as a multifunctioning pleiotropic agent which has a wide range of neuroprotective role in manifold age-related neurodegenerative disorders especially Alzheimer's diseases (AD). AD is a devastating neurodegenerative disorder and common form ...
Santosh Kumar Bose, Prianka Howlader
Melatonin (N-acetyl-5-methoxytryptamine) is a multifunctional nontoxic signaling molecule, universally distributed in different plant organs and accountable for invigorating numerous physiological mechanisms against various adverse environmental factors. In the current review, we revealed that the b...
R Alvarez-Buylla, Elena Roces de Álvarez-Buylla
This paper describes (a) the influence of glucose on carotid chemoreceptor activity, and (b) the participation of carotid receptors in glucose homeostasis. After eliminating the carotid body baroreceptors in anesthetized cats, the injection of glucose to the vascularly isolated carotid sinus region ...
B. D. Green, Nigel Irwin, Peter R. Flatt
Obestatin is a recently discovered peptide hormone that appears to be involved in reducing food intake, gut motility and body weight. Obestatin is a product of the preproghrelin gene and appears to oppose several physiological actions of ghrelin. This study investigated the acute effects of obestati...
Madeleine Gantley, David Davies, Anne Murcott
OBJECTIVES: To investigate infant care practices in a small ethnic minority population within Britain that might suggest possible factors contributing to the low incidence of the sudden infant death syndrome in Asian populations. DESIGN: Ethnographic interviewing, a qualitative comparative method dr...
Tanvir Ahmed, Sai Krupa Das, Julie K. Golden, Edward Saltzman et al.
Calorie restriction (CR) enhances immune response and prolongs life span in animals. However, information on the applicability of these results to humans is limited. T-cell function declines with age. We examined effects of CR on T-cell function in humans. Forty-six overweight, nonobese participants...
Anastasiia D. Shkodina, Shing Cheng Tan, Mohammad Mehedi Hasan, Mai Abdelgawad et al.
Parkinson's disease (PD) is a common motor disorder that has become increasingly prevalent in the ageing population. Recent works have suggested that circadian rhythms disruption is a common event in PD patients. Clock genes regulate the circadian rhythm of biological processes in eukaryotic organis...
Thomas Paparrigopoulos, Antigoni Melissaki, Hara Tsekou, Anna Efthymiou et al.
PRIMARY OBJECTIVE: To investigate the circadian rhythm of serum melatonin in patients with traumatic brain injury (TBI) during Intensive Care Unit (ICU) stay and its relationship with core body temperature fluctuations and measures of severity of their condition. METHODS AND PROCEDURES: The pilot st...
Md. Farhad Hossain, Ni Wang, Ruijun Chen, Siwen Li et al.
Melatonin (MLT) is a neurohormone that is regulated by the circadian clock and plays multifunctional roles in numerous neurodegenerative disorders, such as Alzheimer's disease (AD). Alzheimer's disease is the most common form of dementia and is associated with the degradation of axons and synapses r...
Dmytro I. Boiko, Anastasiia D. Shkodina, Mohammad Mehedi Hasan, Mainak Bardhan et al.
A complex pathogenesis involving several physiological systems is theorized to underline the development of depressive disorders. Depression is accompanied by circadian regulation disruption and interaction with the functioning of both central and peripheral oscillators. Many aspects of melatonin fu...
Sophia M. Moscovis
Uncontrolled pro-inflammatory responses to infections or bacterial toxins have been suggested to play a role in triggering the physiological events leading to sudden infant death syndrome (SIDS). We tested the hypothesis that these uncontrolled responses might be due to interactions between the gene...