Ami D. Sperber, Shrikant I. Bangdiwala, Douglas A. Drossman, Uday C. Ghoshal et al.
BACKGROUND & AIMS Although functional gastrointestinal disorders (FGIDs), now called disorders of gut-brain interaction, have major economic effects on healthcare systems and adversely affect quality of life, little is known about their global prevalence and distribution. We investigated the prevale...
Chayon Goswami, Yusaku Iwasaki, Toshihiko Yada
Fermentable carbohydrates including dietary fibers and resistant starch produce short-chain fatty acids (SCFAs), including acetate, propionate and butyrate, through microbial fermentation in the intestine of rodents and humans. Consumption of fermentable carbohydrate and SCFAs suppress food intake, ...
Masuma Afrin Taniya, Hea‐Jong Chung, Abdullah Al Mamun, Safaet Alam et al.
Autism spectrum disorder (ASD) is a neurological disorder that affects normal brain development. The recent finding of the microbiota-gut-brain axis indicates the bidirectional connection between our gut and brain, demonstrating that gut microbiota can influence many neurological disorders such as a...
Cynthia L. Sears, Salequl Islam, Amit Saha, Maleka Arjumand et al.
BACKGROUND: Diarrheal illnesses remain a leading cause of morbidity and mortality globally, with increasing recognition of long-term sequelae, including postinfectious irritable bowel syndrome and growth faltering, as well as cognitive deficits in children. Identification of specific etiologic agent...
MohammedA Masud, Mahmud Hasan, A. K. Azad Khan
OBJECTIVE: The aim of this study was to investigate the prevalence of irritable bowel syndrome (IBS) and the pattern of symptoms and health care seeking behavior of IBS subjects in the rural population in Bangladesh. METHODS: This was an observational study to do a positive diagnosis of IBS. A total...
Doreen McClurg, Suzanne Hagen, Stanley Hawkins, Andrea Lowe-Strong
BACKGROUND: Constipation affects many people with multiple sclerosis (MS), negatively impacting on their quality of life. The use of abdominal massage has been reported in several populations and has been shown to increase the frequency of defaecation. OBJECTIVE: The objective of this study was to d...
Uday C. Ghoshal, Ujjala Ghoshal, M. Masudur Rahman, Akash Mathur et al.
BACKGROUND AND AIM: Because acute infectious gastroenteritis may cause post-infection irritable bowel syndrome and functional dyspepsia and the severe acute respiratory syndrome coronavirus-2 affects gastrointestinal (GI) tract, coronavirus disease-19 (COVID-19) may cause post-infection-functional G...
S M Ishaque, Sheikh Mohammed Khosruzzaman, Dewan Saifuddin Ahmed, Mukesh Prasad Sah
BACKGROUND: Accumulating evidence supports the view that an imbalance of gut bacteria contributes to IBS, and that increasing the mass of beneficial species may reduce the numbers of pathogenic bacteria and help alleviate symptoms. METHODS: In this double-blind trial 400 adult patients with moderate...
Ta‐Chiang Liu, Kelley VanBuskirk, Asad Ali, Paul Kelly et al.
BACKGROUND: A major limitation to understanding the etiopathogenesis of environmental enteric dysfunction (EED) is the lack of a comprehensive, reproducible histologic framework for characterizing the small bowel lesions. We hypothesized that the development of such a system will identify unique his...
Uday C. Ghoshal, Sanjeev Sachdeva, Ujjala Ghoshal, Asha Misra et al.
In the clinical setting, small intestinal bacterial overgrowth (SIBO) is a frequent, but under-diagnosed entity. SIBO is linked to various gastrointestinal (GI) and non-GI disorders with potentially significant morbidity. The optimal management of SIBO is undefined while there is a lack of published...
Dilip Mahalanabis, M. Masudur Rahman, Shafiqul Alam Sarker, Pradip Kumar Bardhan et al.
BACKGROUND: The gastric acid barrier, an important host defence against small bowel infection, may be compromised by infection with Helicobacter pylori. In developing countries, H. pylori infection occurs early in life and prevalence of hypochlorhydria is high particularly in the malnourished, which...
Sarmistha Mitra, Raju Dash, Amena Al Nishan, Sarmin Ummey Habiba et al.
BACKGROUND: The gut microbiota (GM) and brain are strongly associated, which significantly affects neuronal development and disorders. GM-derived metabolites modulate neuronal function and influence many cascades in age-related neurodegenerative disorders (NDDs). Because of the dual role of GM in ne...
Noor Akram, Zargham Faisal, Rushba Irfan, Yasir Abbas Shah et al.
Modulatory effects of serotonin (5-Hydroxytryptamine [5-HT]) have been seen in hepatic, neurological/psychiatric, and gastrointestinal (GI) disorders. Probiotics are live microorganisms that confer health benefits to their host. Recent research has suggested that probiotics can promote serotonin sig...
Jeffrey R. Donowitz, Rashidul Haque, Beth D. Kirkpatrick, Masud Alam et al.
UNLABELLED: Recent studies suggest small intestine bacterial overgrowth (SIBO) is common among developing world children. SIBO's pathogenesis and effect in the developing world are unclear. Our objective was to determine the prevalence of SIBO in Bangladeshi children and its association with malnutr...
M. Masudur Rahman, Sanjiv Mahadeva, Uday C. Ghoshal
Irritable bowel syndrome (IBS) is a chronic gastrointestinal disorder, common in clinic and in the community. It has a significant impact on both society and patients' quality of life. The epidemiology, clinical presentation, and management of IBS may vary in different geographical regions due to di...