Shafiqul Alam Sarker, Lena Davidsson, Hasan Mahmud, Thomas Walczyk et al.
Background Nonheme-iron absorption requires an acidic milieu. Reduced gastric acid output as a consequence of Helicobacter pylori infection could be an important limiting factor for iron absorption. Objective We measured gastric acid output and iron absorption from a non-water-soluble iron compound ...
Shafiqul Alam Sarker, Hasan Mahmud, Lena Davidsson, Nur Alam et al.
Background & aims We investigated Helicobacter pylori (H pylori)-infection as a cause of iron deficiency (ID) and iron-deficiency anemia (IDA) or treatment failure of iron supplementation. Methods We randomized 200 Hp-infected children (positive urea breath test) 2-5 years of age with IDA (hemoglobi...
Mian Mashhud Ahmad, Mahbubur Rahman, Azharul Karim Rumi, Shafiqul Islam et al.
Epidemiological reports reveal that H. pylori is distributed among all population in the world. The present cross-sectional study was undertaken to see the H. pylori seroprevalence rates among the asymptomatic adults, as yet reportedly no such data available in Bangladesh. Serum samples were collect...
Shamsun Nahar, Asish K. Mukhopadhyay, Rasel Khan, Mian Mashhud Ahmad et al.
Antimicrobial susceptibility of 120 Helicobacter pylori isolates to metronidazole, tetracycline, clarithromycin, and amoxicillin was determined, and 77.5, 15, 10, and 6.6% of the isolates, respectively, were resistant. Only rdxA inactivation and both rdxA and frxA inactivation were responsible for m...
Dilip Mahalanabis, M. Masudur Rahman, Shafiqul Alam Sarker, Pradip Kumar Bardhan et al.
BACKGROUND: The gastric acid barrier, an important host defence against small bowel infection, may be compromised by infection with Helicobacter pylori. In developing countries, H. pylori infection occurs early in life and prevalence of hypochlorhydria is high particularly in the malnourished, which...
Valeria García-Castillo, Ryoya Komatsu, Patricia Clua, Yuhki Indo et al.
Lactobacillus fermentum UCO-979C, a strain isolated from a human stomach, was previously characterized by its potential probiotic properties. The UCO-979C strain displayed the ability to beneficially regulate the innate immune response triggered by Helicobacter pylori infection in human gastric epit...
JD Clemens, M. John Albert, Malla Rao, Firdausi Qadri et al.
To evaluate the relationship between Helicobacter pylori infection and the subsequent risk and severity of endemic Vibrio cholerae O1 diarrhea among rural Bangladeshis, 285 children and adults with cholera (cases) and 881 contemporaneously selected community controls were studied. Cases and controls...
Kaisa Thorell, Zilia Y. Muñoz-Ramírez, Difei Wang, Santiago Sandoval‐Motta et al.
Helicobacter pylori, a dominant member of the gastric microbiota, shares co-evolutionary history with humans. This has led to the development of genetically distinct H. pylori subpopulations associated with the geographic origin of the host and with differential gastric disease risk. Here, we provid...
J. Athene Lane, Liam Murray, Sian Noble, Matthias Egger et al.
OBJECTIVE: To determine the impact of a community based Helicobacter pylori screening and eradication programme on the incidence of dyspepsia, resource use, and quality of life, including a cost consequences analysis. DESIGN: H pylori screening programme followed by randomised placebo controlled tri...
Md. Al-Mustanjid, Saifuddin Mahmud, Md. Rejaul Islam Royel, Md. Habibur Rahman et al.
Emerging evidence indicates IBD is a risk factor for the increasing incidence of colorectal cancer (CRC) development. We used a system biology approach to identify common molecular signatures and pathways that interact between IBD and CRC and the indispensable pathological mechanisms. First, we iden...
Md. Amjad Hossen, A.S.M. Ali Reza, A. M. Abu Ahmed, Md. Kamrul Islam et al.
Blumea lacera (Burm.f.) DC. is described as a valuable medicinal plant in various popular systems of medicine. The aim of the experiment reports the in vivo antiulcer activity of methanol extract of Blumea lacera (MEBLL) and in silico studies of bioactive constituents of MEBLL. In this study, fasted...
Anders Janzon, Åsa Sjöling, Åsa Lothigius, Dilruba Ahmed et al.
The main transmission pathway of Helicobacter pylori has not been determined, but several reports have described detection of H. pylori DNA in drinking and environmental water, suggesting that H. pylori may be waterborne. To address this possibility, we developed, tested, and optimized two complemen...
Simanti Datta, Santanu Chattopadhyay, Rajashree Patra, Ronita De et al.
BACKGROUND: Helicobacter pylori infection is very common in India, as in other developing countries, but few data exist on the susceptibility of H. pylori to antimicrobial agents commonly used for eradication here. AIM: To determine the antimicrobial susceptibility of H. pylori strains from Kolkata,...
Rasel Khan, Shamsun Nahar, Jinath Sultana, Mian Mashhud Ahmad et al.
Twelve clarithromycin-resistant (MIC, > or = 1 microg/ml) Helicobacter pylori isolates were analyzed for point mutations in the 23S rRNA gene. Sequence analysis of all of the resistant isolates revealed a T-to-C transition mutation at position 2182. Transformation experiments confirmed that a single...
Santanu Chattopadhyay, Simanti Datta, Abhijit Chowdhury, Sujit Chowdhury et al.
We compared putative molecular markers of virulence (vacA, cagA, and iceA) of Helicobacter pylori strains isolated from 52 adult duodenal ulcer patients from West Bengal, India, with those of H. pylori strains isolated from 48 adult healthy volunteers from the same region. On the basis of genotyping...