Md Mizanur Rahman, Sarah Krull Abe, Md. Shafiur Rahman, Mikiko Kanda et al.
Background Anemia is a leading cause of maternal deaths and adverse pregnancy outcomes in developing countries. Objectives We conducted a systematic review and meta-analysis to estimate the pooled prevalence of anemia, the association between maternal anemia and pregnancy outcomes, and the populatio...
Sriram Krishnaswamy, W R Church, Michael E. Nesheim, Kenneth G. Mann
The kinetics of the activation of human prothrombin catalyzed by human prothrombinase was studied using the fluorescent alpha-thrombin inhibitor dansylarginine-N-(3-ethyl-1,5-pentanediyl)amide (DAPA). Prothrombinase proteolytically activates prothrombin to alpha-thrombin by cleavages at Arg273-Thr27...
Jahidur Rahman Khan, Nabil Awan, Farjana Misu
BACKGROUND: Anemia is a global public health problem but the burden of anemia is disproportionately borne among children in developing countries. Anemia in early stages of life has serious consequences on the growth and development of the children. We examine the prevalence of anemia, possible assoc...
Lars Åke Persson, Shams El Arifeen, Eva‐Charlotte Ekström, Kathleen M. Rasmussen et al.
CONTEXT: Nutritional insult in fetal life and small size at birth are common in low-income countries and are associated with serious health consequences. OBJECTIVES: To test the hypothesis that prenatal multiple micronutrient supplementation (MMS) and an early invitation to food supplementation woul...
Caroline Fall, David J. Fisher, Clive Osmond, Barrie Margetts
BACKGROUND: Multiple micronutrient deficiencies are common among women in low-income countries and may adversely affect pregnancy outcomes. OBJECTIVE: This meta-analysis reports the effects on newborn size and duration of gestation of multiple micronutrient supplementation mainly compared with iron ...
Jenny Jung, Md Mizanur Rahman, Md. Shafiur Rahman, Khin Thet Swe et al.
Maternal anemia affects approximately 56 million women worldwide and increases the risk of adverse pregnancy outcomes. Our study aimed to summarize the evidence for the association between maternal hemoglobin (Hb) concentrations and maternal or infant outcomes, evaluating it in a continuous manner. ...
Dev Ram Sunuwar, Devendra Raj Singh, Narendra Kumar Chaudhary, Pranil Man Singh Pradhan et al.
BACKGROUND: Anemia remains a major public health challenge with high prevalence among women in South and Southeast Asian countries. Reductions in anemia rates have been stalled, despite the implementation of different maternal health and nutrition programs. This study aimed to assess the prevalence ...
Alok Bhargava, Howarth E. Bouis, Nevin S. Scrimshaw
Iron deficiency anemia affects a large number of women in developing countries, especially during child-bearing years. The hemoglobin concentration is useful for identifying iron deficiency anemia. The main objectives of this study were, first, to extend algorithms for calculating bioavailable iron ...
S.M. Ziauddin Hyder, Lars Åke Persson, Rajiv Chowdhury, Eva‐Charlotte Ekström
Side-effects of iron supplementation lead to poor compliance. A weekly-dose schedule of iron supplementation rather than a daily-dose regimen has been suggested to produce fewer side-effects, thereby achieving a higher compliance. This study compared side-effects of iron supplementation and their im...
Saul S. Morris, Marie T. Ruel, Roberta J. Cohen, Kathryn G Dewey et al.
Background Previous research has suggested that there may be significant within-subject variability, both site-to-site and over time, in hemoglobin concentrations in capillary blood. Objective This study examined the reliability of the portable hemoglobinometer (PHM) system with use of capillary blo...
Mohammad Shafiqur Rahman, Muntaha Mushfiquee, Mohammad Shahed Masud, Tamanna Howlader
BACKGROUND: Bangladesh is one of the most anemia prone countries in South Asia. Children of age under five years and women of reproductive age are particularly vulnerable in this region. Although several studies have investigated the risk factors of anemia, only few have explored its association wit...
Kerry Schulze, Sucheta Mehra, Saijuddin Shaikh, Hasmot Ali et al.
BACKGROUND: Antenatal multiple micronutrient (MM) supplementation improves birth outcomes relative to iron-folic acid (IFA) in developing countries, but limited data exist on its impact on pregnancy micronutrient status. OBJECTIVE: We assessed the efficacy of a daily MM (15 nutrients) compared with ...
Oscar Lindblad, Eugenia Cordero, Alexandre Puissant, L Macaulay et al.
Therapy directed against oncogenic FLT3 has been shown to induce response in patients with acute myeloid leukemia (AML), but these responses are almost always transient. To address the mechanism of FLT3 inhibitor resistance, we generated two resistant AML cell lines by sustained treatment with the F...
B A Wharton
Despite a plethora of papers, reports and consensus statements during the last 25 years concerning the high prevalence and complications of iron deficiency (ID), the problem is still with us. A recent national study in Britain showed that 12% of 2-year-olds were anaemic, rising to 29% in Asian immig...
Faruk Ahmed, Moududur Rahman Khan, Alan A. Jackson
Background Iron deficiency is the most common micronutrient deficiency and affects >2 billion persons worldwide, leading to anemia in >40% of women of reproductive age in the developing world. Objective The objective was to determine whether weekly supplementation with iron and folate would reduce t...