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16+ results
Field: Heme Oxygenase-1 and Carbon Monoxide

Role of Nrf2-mediated heme oxygenase-1 upregulation in adaptive survival response to nitrosative stress

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Young‐Joon Surh, Joydeb Kumar Kundu, Meihua Li, Hye‐Kyung Na et al.

Journal: Archives of Pharmacal Research
Year: 2009
Citations: 121

Nitrosative stress caused by reactive nitrogen species such as nitric oxide and peroxynitrite overproduced during inflammation leads to cell death and has been implicated in the pathogenesis of many human ailments. However, relatively mild nitrosative stress may fortify cellular defense capacities, ...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular Biology
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Prevalence of smokeless tobacco use among adults in WHO South-East Asia

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DN Sinha, PC Gupta, CS Ray, PK Singh

Journal: Indian Journal of CancerYear: 2012Citations: 116

Smokeless tobacco (SLT) use is an understudied problem in South-East Asia. Information on SLT use among the adult population was collected from various available sources. SLT use prevalence varies among countries in the region. The prevalence of SLT use is known for all countries at national level i...

Health SciencesMedicinePhysiology
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Pharmacotherapy against Oxidative Stress in Chronic Kidney Disease: Promising Small Molecule Natural Products Targeting Nrf2-HO-1 Signaling

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Md Jamal Uddin, Ee Hyun Kim, Md. Abdul Hannan, Hunjoo Ha

Journal: AntioxidantsYear: 2021Citations: 104

The global burden of chronic kidney disease (CKD) intertwined with cardiovascular disease has become a major health problem. Oxidative stress (OS) plays an important role in the pathophysiology of CKD. The nuclear factor erythroid 2-related factor 2 (Nrf2)-antioxidant responsive element (ARE) antiox...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Lycopene Triggers Nrf2–AMPK Cross Talk to Alleviate Atrazine-Induced Nephrotoxicity in Mice

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Jia Lin, Jun Xia, Hua-Shan Zhao, Rui Hou et al.

Journal: Journal of Agricultural and Food ChemistryYear: 2018Citations: 94

Atrazine (ATR), an environmental persistent and bioaccumulative herbicide, has been associated with environmental nephrosis. Lycopene (LYC) exhibits important properties of nephroprotection, but there are limited data on the specific underlying mechanism. The primary objective of this study was to e...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular Biology
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Role of Pyroptosis in Diabetes and Its Therapeutic Implications

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Abdullah Al Mamun, Yanqing Wu, Fatema Nasrin, Afroza Akter et al.

Journal: Journal of Inflammation ResearchYear: 2021Citations: 83

Pyroptosis is mainly considered as a new pro-inflammatory mediated-programmed cell death. In addition, pyroptosis is described by gasdermin-induced pore formation on the membrane, cell swelling and rapid lysis, and several pro-inflammatory mediators interleukin-1β (IL-1β) and interleukin-18 (IL-18) ...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Pyroptosis in diabetic nephropathy

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Abdullah Al Mamun, Anjuman Ara Mimi, Yanqing Wu, Muhammad Zaeem et al.

Journal: Clinica Chimica ActaYear: 2021Citations: 78

Diabetic nephropathy (DN), a sterile inflammatory disease, is a serious complication common to diabetes mellitus. Recent evidence indicates that pyroptosis, a new term for pro-inflammatory cell death featured by gasdermin D (GSDMD)-stimulated plasma membrane pore generation, cell expansion and rapid...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular Biology
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A systematic review and meta-analysis of intraday effects of ambient air pollution and temperature on cardiorespiratory morbidities: First few hours of exposure matters to life

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Keyu Wu, Hung Chak Ho, Hong Su, Cunrui Huang et al.

Journal: EBioMedicineYear: 2022Citations: 56

BACKGROUND: A growing number of studies have reported an increased risk of cardiovascular disease (CVD) and respiratory disease (RD) within hours after exposure to ambient air pollution or temperature. We assemble published evidence on the sub-daily associations of CVD and RD with ambient air pollut...

Physical SciencesEnvironmental ScienceHealth, Toxicology and MutagenesisOpen Access
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Elevated levels of plasma uric acid and its relation to hypertension in arsenic-endemic human individuals in Bangladesh

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Nazmul Huda, Shakhawoat Hossain, Mashiur Rahman, Md. Rezaul Karim et al.

Journal: Toxicology and Applied PharmacologyYear: 2014Citations: 52

Blood uric acid has been recognized as a putative marker for cardiovascular diseases (CVDs). CVDs are the major causes of arsenic-related morbidity and mortality. However, the association of arsenic exposure with plasma uric acid (PUA) levels in relation to CVDs has not yet been explored. This study...

Health SciencesMedicineNephrology
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Disparities in smokeless tobacco use in Bangladesh, India, and Pakistan: Findings from the Global Adult Tobacco Survey, 2014-2017

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Luhua Zhao, Lazarous Mbulo, Evelyn Twentyman, Krishna Palipudi et al.

Journal: PLoS ONEYear: 2021Citations: 47

BACKGROUND: Smokeless tobacco (SLT) use is associated with multiple adverse health effects. It is prominent in Bangladesh, India, and Pakistan, but disparities in use within and across these countries are not well documented or understood. This study assessed the prevalence, patterns, and correlates...

Health SciencesMedicinePhysiologyOpen Access
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Role of pyroptosis in diabetic retinopathy and its therapeutic implications

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Abdullah Al Mamun, Anjuman Ara Mimi, Muhammad Zaeem, Yanqing Wu et al.

Journal: European Journal of PharmacologyYear: 2021Citations: 46

Pyroptosis has recently been established as a term of programmed-inflammatory cell death. Pyroptosis is mainly divided into two molecular signaling pathways, including caspase-1-dependent canonical and caspase-4/5/11-dependent non-canonical inflammasome pathways. Extensive investigations have report...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular Biology
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Lycopene ameliorates DEHP exposure-induced renal pyroptosis through the Nrf2/Keap-1/NLRP3/Caspase-1 axis

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Muzi Li, Yi Zhao, Xueyan Dai, Milton Talukder et al.

Journal: The Journal of Nutritional BiochemistryYear: 2023Citations: 36

Di (2-ethylhexyl) phthalate (DEHP) is commonly used as a plasticizer in plastic products, and due to its unique chemical composition, it frequently dissolves and enters the environment. Lycopene as a natural carotenoid has been shown to have powerful antioxidant capacity and strong kidney protection...

Health SciencesMedicineNephrology
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Curcuma longa rhizome extract and Curcumin reduce the adhesion of Acanthamoeba triangularis trophozoites and cysts in polystyrene plastic surface and contact lens

Verified

Watcharapong Mitsuwan, Suthinee Sangkanu, Chonticha Romyasamit, Chalermpon Kaewjai et al.

Journal: International Journal for Parasitology Drugs and Drug ResistanceYear: 2020Citations: 33

Curcuma longa and Curcumin have been documented to have a wide spectrum of pharmacological effects, including anti-Acanthamoeba activity. Hence, this study sought to explore the anti-adhesion activity of C. longa extract and Curcumin against Acanthamoeba triangularis trophozoites and cysts in plasti...

Life SciencesBiochemistry, Genetics and Molecular BiologyEndocrinologyOpen Access
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Reversible oxygenation

Verified

R. W. Erskine, B. O. Field

Journal: Structure and bondingYear: 1976Citations: 31
Life SciencesBiochemistry, Genetics and Molecular BiologyCell Biology
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An epidemic survey on freshwater puffer poisoning in Bangladesh.

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Yahia Mahmud, Osamu Arakawa, T Noguchi

Journal: PubMedYear: 2000Citations: 30

An epidemic investigation was carried out on freshwater puffer poisoning incidents in Bangladesh from April 1988 to May 1996. A lot of information on 10 poisoning cases involving 55 victims was collected through newspapers, interviewing the victims and their families, concerned hospital sources or q...

Health SciencesMedicineNeurology
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Natural Flavonoids as Primary Amoebic Meningoencephalitis Inhibitor: Virtual Screening, Molecular Docking, MD Simulation, MMPBSA, Density Functional Theory, Principal Component, and Gibbs Free Energy Landscape Analyses

Verified

Supriyo Saha, Prinsa Prinsa, Sarkar M. A. Kawsar

Journal: Chemistry & BiodiversityYear: 2024Citations: 27

ABSTRACT Flavonoids have been showing diversified bioactivities. Primary amoebic meningoencephalitis is a brain inflammation caused by Naegleria fowleri brain eating amoeba. In this manuscript, we selected 93 flavonoids by extensive literature survey and 83 flavonoids passed drug likeness parameter....

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular MedicineOpen Access
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