Yang Dong, Lin Hao, Zhenduo Shi, Gang Wang et al.
OBJECTIVE: To evaluate the efficacy and safety of tadalafil monotherapy for lower urinary tract symptoms secondary to benign prostatic hyperplasia (LUTS/BPH). METHODS: A comprehensive search was done to identify randomized controlled trials comparing the efficacy and safety of tadalafil for LUTS/BPH...
Wei Gao, Tobias Stalder, Paul Foley, Manfred Rauh et al.
The analysis of steroid hormones in hair is increasingly used in the field of stress-related research to obtain a retrospective index of integrated long-term hormone secretion. Here, most laboratories have so far relied on immunochemical assays originally developed for salivary analyses. Although th...
Rebecca C. Miller, Eleanor Brindle, Darryl J. Holman, Jane B. Shofer et al.
BACKGROUND: Specific gravity (SG) may perform as well as creatinine (CR) correction for adjusting urinary hormone concentrations, as well as offer some advantages. We compared the two methods and applied them to US and Bangladeshi specimens to evaluate their use in different populations. METHODS: Pe...
Iñigo Sáenz de Tejada, Javier Angulo, Selim Cellek, Néstor F. González-Cadavid et al.
INTRODUCTION: Multiple regulatory systems are involved in normal erectile function. Disruption of psychological, neurological, hormonal, vascular, and cavernosal factors, individually, or in combination, can induced erectile dysfunction (ED). The contribution of neurogenic, vascular, and cavernosal ...
Kathleen O’Connor, Eleanor Brindle, Darryl J. Holman, Nancy A. Klein et al.
BACKGROUND: Monitoring of reproductive steroid hormones at the population level requires frequent measurements, hormones or metabolites that remain stable under less than ideal collection and storage conditions, a long-term supply of antibodies, and assays useful for a range of populations. We devel...
Shah Ebrahim, M May, Y Ben Shlomo, P McCarron et al.
OBJECTIVE: To examine the relation between frequency of sexual intercourse and risk of ischaemic stroke and coronary heart disease. DESIGN: Cohort study with 20 year follow up. SETTING: The town of Caerphilly, South Wales and five adjacent villages. SUBJECTS: 914 men aged 45-59 years at time of recr...
Janet Heaton, Jason W. Dean, Darryl J. Sleep
The response to Uprima (apomorphine sublingual, (apo SL)) has been well documented in conventional clinical trials. Apo SL produces a predictable, consistent and durable response across a wide variety of patients. The positive reinforcement of a successful outcome should further support clinical ben...
Christopher R. Chapple, M. STOTT, Paul Abrams, T. J. CHRISTMAS et al.
A series of 93 normotensive patients with benign prostatic hyperplasia and maximum urinary flow rates < 15 ml/s, treated at 2 hospital centres using an identical protocol, was randomly assigned to receive a 12-week course of treatment with prazosin or placebo in a double-blind parallel group trial. ...
Martin Steggall
Abstract Erectile dysfunction is a common sexual problem in men that can result in poor self‐image and depression. There is growing evidence linking erectile dysfunction and cardiovascular disease. The author discusses the risk factors, diagnosis and the treatment options available, and describes th...
Catriona Duncan, Ghadir Omran, Jiasian Teh, Niall F. Davis et al.
Purpose Data assessing the effectiveness of intracavernosal injections (ICIs) for the treatment of erectile dysfunction (ED) are limited. This study evaluates intracavernosal injectable therapies for ED and reviews available guidelines that inform clinical practice. Methods A systematic search using...
M. STOTT, Paul Abrams
A series of 40 patients took part in a double-blind, placebo-controlled trial of indoramin in prostatic bladder outflow obstruction. Patients were assessed clinically and urodynamically before and after 4 weeks' treatment. Significant improvement was seen in nocturia, volume voided, flow rates and r...
S. George Carruthers, Abhisek Ghosal, D. G. McDevitt, J. K. Nelson et al.
1 Intravenous propranolol and practolol both reduced resting supine heart rate in patients with hyperthyroidism. Propranolol produced a significantly greater reduction than practolol, which did not have a dose-dependent effect. 2 The effect of these drugs on resting heart rate was much less than the...
C. KADOW, R. C. L. FENELEY, Paul Abrams
A randomised, prospective trial comparing transurethral prostatectomy with conservative management was carried out in 38 men with proven bladder outflow obstruction. Patients were assessed urodynamically before treatment and 6 months later. All 21 patients who had a prostatectomy showed a significan...
Rakibul M. Islam, Robin J. Bell, Farwa Rizvi, Susan R. Davis
OBJECTIVE: There is a belief that menopausal symptoms, particularly vasomotor symptoms (VMS), are a Western phenomena and less likely to be experienced in women in Asian countries. This systematic review of the literature was undertaken to evaluate the prevalence of VMS in Asian countries. METHODS: ...
Tanvir Kabir Chowdhury, Kamrun Laila, John M. Hutson, Tahmina Banu
Background/aim Girls with congenital adrenal hyperplasia (CAH) diagnosed at birth have some masculine behaviors but rarely convert to male gender. In developing countries, however, diagnosis and treatment (with secondary androgen suppression) are delayed. We aimed to assess effect of delayed treatme...