Ying‐Ying Zheng, Yi‐Tong Ma, Jinying Zhang, Xiang Xie
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects host cells through ACE2 receptors, leading to coronavirus disease (COVID-19)-related pneumonia, while also causing acute myocardial injury and chronic damage to the cardiovascular system. Therefore, particular attention should be g...
Elizabeth A. Ashley, Mehul Dhorda, Rick M. Fairhurst, Chanaki Amaratunga et al.
BACKGROUND: Artemisinin resistance in Plasmodium falciparum has emerged in Southeast Asia and now poses a threat to the control and elimination of malaria. Mapping the geographic extent of resistance is essential for planning containment and elimination strategies. METHODS: Between May 2011 and Apri...
Igor Rudan
Childhood pneumonia is the leading single cause of mortality in children aged less than 5 years. The incidence in this age group is estimated to be 0.29 episodes per child-year in developing and 0.05 episodes per child-year in developed countries. This translates into about 156 million new episodes ...
Sathish Subramanian, Sayeeda Huq, Tanya Yatsunenko, Rashidul Haque et al.
Therapeutic food interventions have reduced mortality in children with severe acute malnutrition (SAM), but incomplete restoration of healthy growth remains a major problem. The relationships between the type of nutritional intervention, the gut microbiota, and therapeutic responses are unclear. In ...
Khalequz Zaman, Eliza Roy, Shams El Arifeen, Mahbubur Rahman et al.
BACKGROUND: Young infants and pregnant women are at increased risk for serious consequences of influenza infection. Inactivated influenza vaccine is recommended for pregnant women but is not licensed for infants younger than 6 months of age. We assessed the clinical effectiveness of inactivated infl...
Subrata Kumar Biswas
Oxidative stress has been implicated in many chronic diseases. However, antioxidant trials are so far largely unsuccessful as a preventive or curative measure. Chronic low-grade inflammatory process, on the other hand, plays a central role in the pathogenesis of a number of chronic diseases. Oxidati...
Nicholas J. White, Sasithon Pukrittayakamee, Tran Tinh Hien, M. Abul Faiz et al.
Although global morbidity and mortality have decreased substantially, malaria, a parasite infection of red blood cells, still kills roughly 2000 people per day, most of whom are children in Africa. Two factors largely account for these decreases; increased deployment of insecticide-treated bednets a...
Firdausi Qadri, Ann–Mari Svennerholm, Shah M. Faruque, R. Bradley Sack
ETEC is an underrecognized but extremely important cause of diarrhea in the developing world where there is inadequate clean water and poor sanitation. It is the most frequent bacterial cause of diarrhea in children and adults living in these areas and also the most common cause of traveler's diarrh...
James A Platts-Mills, Sudhir Babji, Ladaporn Bodhidatta, Jean Gratz et al.
BACKGROUND: Most studies of the causes of diarrhoea in low-income and middle-income countries have looked at severe disease in people presenting for care, and there are few estimates of pathogen-specific diarrhoea burdens in the community. METHODS: We undertook a birth cohort study with not only int...
Rashidul Haque, Christopher D. Huston, Molly A. Hughes, Eric R. Houpt et al.
Infection with Entamoeba histolytica can lead to amebic colitis and to complications including liver abscess. This review summarizes recent research on the pathogenesis and treatment of infection and the prospects for the development of a vaccine. A mucosal IgA response can produce partial, protecti...
Md. Tanvir Rahman, Md. Abdus Sobur, Md. Saiful Islam, Samina Ievy et al.
Most humans are in contact with animals in a way or another. A zoonotic disease is a disease or infection that can be transmitted naturally from vertebrate animals to humans or from humans to vertebrate animals. More than 60% of human pathogens are zoonotic in origin. This includes a wide variety of...
Md. Abul Kalam Azad, Manobendro Sarker, Tiejun Li, Jie Yin
Probiotics are microbial strains that are beneficial to health, and their potential has recently led to a significant increase in research interest in their use to modulate the gut microbiota. The animal gut is a complex ecosystem of host cells, microbiota, and available nutrients, and the microbiot...
Md. Mominur Rahman, Md. Saidur Rahaman, Md. Rezaul Islam, Firoza Rahman et al.
Inflammation is a natural protective mechanism that occurs when the body's tissue homeostatic mechanisms are disrupted by biotic, physical, or chemical agents. The immune response generates pro-inflammatory mediators, but excessive output, such as chronic inflammation, contributes to many persistent...
Elaine Robertson, Kelly S Reeve, Claire L. Niedzwiedz, Jamie Moore et al.
Vaccine hesitancy could undermine efforts to control COVID-19. We investigated the prevalence of COVID-19 vaccine hesitancy in the UK and identified vaccine hesitant subgroups. The 'Understanding Society' COVID-19 survey asked participants (n = 12,035) their likelihood of vaccine uptake and reason f...
Armand Van Deun, Aung Kya Jai Maug, Md Abdul Hamid Salim, Pankaj Das et al.
RATIONALE: Based on expert opinion, the global guidelines for management of multidrug-resistant tuberculosis impose lengthy and often poorly tolerated treatments. OBJECTIVES: This observational study evaluates the effectiveness of standardized regimens for patients with proven multidrug-resistant tu...