Sabeena Ahmed, Mohammad Mahbubul Karim, Allen G. Ross, Mohammad Hossain et al.
Ivermectin, a US Food and Drug Administration-approved anti-parasitic agent, was found to inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication in vitro. A randomized, double-blind, placebo-controlled trial was conducted to determine the rapidity of viral clearance and saf...
Anand Joshi, Murari Lal Das, Shireen Akhter, Rajib Chowdhury et al.
BACKGROUND: Bangladesh, India and Nepal are working towards the elimination of visceral leishmaniasis (VL) by 2015. In 2005 the World Health Organization/Training in Tropical Diseases launched an implementation research programme to support integrated vector management for the elimination of VL from...
Siddhivinayak Hirve, Marleen Boelaert, Greg Matlashewski, Dinesh Mondal et al.
BACKGROUND: As Bangladesh, India and Nepal progress towards visceral leishmaniasis (VL) elimination, it is important to understand the role of asymptomatic Leishmania infection (ALI), VL treatment relapse and post kala-azar dermal leishmaniasis (PKDL) in transmission. METHODOLOGY/ PRINCIPAL FINDING:...
Md Gulam Musawwir Khan, Khondaker Rifat Hasan Bhaskar, Md. Abdus Salam, Tania Akther et al.
BACKGROUND: Visceral leishmaniasis (VL) remains as one of the most neglected tropical diseases with over 60% of the world's total VL cases occurring in the Indian subcontinent. Due to the invasive risky procedure and technical expertise required in the classical parasitological diagnosis, the goal o...
Siddhivinayak Hirve, Axel Kroeger, Greg Matlashewski, Dinesh Mondal et al.
BACKGROUND: The decade following the Regional Strategic Framework for Visceral Leishmaniasis (VL) elimination in 2005 has shown compelling progress in the reduction of VL burden in the Indian subcontinent. The Special Programme for Research and Training in Tropical Diseases (TDR), hosted by the Worl...
Tamer H. Farag, Abu S. G. Faruque, Yukun Wu, Sumon Kumar Das et al.
BACKGROUND: Shigella infections are a public health problem in developing and transitional countries because of high transmissibility, severity of clinical disease, widespread antibiotic resistance and lack of a licensed vaccine. Whereas Shigellae are known to be transmitted primarily by direct feca...
Dinesh Mondal, Jorge Alvar, Md Golam Hasnain, Md Shakhawat Hossain et al.
BACKGROUND: To rapidly reduce the burden of visceral leishmaniasis for national elimination programmes, an acceptable, safe, and effective treatment is needed that can be delivered at primary health-care centres. We aimed to assess the tolerability, safety, and cure rate of single-dose liposomal amp...
Ramesh C. Dhiman, Rajpal S. Yadav
BACKGROUND: Visceral leishmaniasis, commonly known as kala-azar in India, is a global public health problem. In Southeast Asia, Bangladesh, Bhutan, India, Nepal, Sri Lanka and Thailand are endemic for visceral leishmaniasis. The role of sandflies as the vector of kala-azar was first confirmed in 194...
Diwakar Singh Dinesh, Pradeep Das, Albert Picado, Clive R. Davies et al.
OBJECTIVE: To determine whether the use of long-lasting insecticidal nets (LLINS) at household level are effective in reducing the abundance of Phlebotomus argentipes, vector of anthroponotic visceral leishmaniasis in India, Nepal and Bangladesh. METHODS: The impact of two long-lasting nets (Olyset ...
Sharmin Akter, Abdullah Al Momen Sabuj, Zobayda Farzana Haque, Md. Tanvir Rahman et al.
Background and Aim: Houseflies (Musca domestica) are synanthropic insects which serve as biological or mechanical vectors for spreading multidrug-resistant bacteria responsible for many infectious diseases. This study aimed to detect antibiotic-resistant bacteria from houseflies, and to examine thei...
Margriet den Boer, Asish Kumar Das, Fatima Akhter, Sakib Burza et al.
Background: A safe and effective short-course treatment regimen for post-kala-azar dermal leishmaniasis (PKDL) is considered essential for achieving and sustaining elimination of visceral leishmaniasis (VL) in the Indian subcontinent [1, 2]. Here, single-dose liposomal amphotericin B (AmBisome) has ...
Rajib Chowdhury, Vijay Kumar, Dinesh Mondal, Murari Lal Das et al.
BACKGROUND: Visceral leishmaniasis (VL), also known as kala-azar in the Indian sub-continent (ISC), is a major public health concern in Bangladesh, India, and Nepal, where it is caused by Leishmania donovani transmitted by the sand fly Phlebotomus argentipes. Various ecological parameters including ...
Dinesh Mondal, Mohammad Shafiul Alam, Zehadul Karim, Rashidul Haque et al.
Objectives Kala-azar or visceral leishmaniasis is one of the major vector-borne diseases in Bangladesh. The disease is transmitted by sandfly. The incidence of the disease, which has been increasing since the early eighties, must be reduced by taking adequate vector-control measures. The objective o...
Yrja Lisa Lindeberg, Karen Egedal, Zenat Zebin Hossain, Matthew Phelps et al.
OBJECTIVE: To investigate the transmission of faecal bacteria by flies to food under natural settings. METHODS: Over a period of 2 months, paired (exposed and non-exposed) containers with cooked rice were placed on the ground in kitchen areas in an urban slum area in Dhaka, Bangladesh, and the numbe...
Anna Eichenberger, Annina E. Buechi, Andreas Neumayr, Chistroph Hatz et al.
BACKGROUND: Visceral leishmaniasis (VL) is a protozoan disease, which is responsible for 200.000-400.000 yearly infections worldwide. If left untreated, the fatality rate can be as high as 100% within 2 years. 90% of cases occur in just six countries: India, Bangladesh, Sudan, South Sudan, Ethiopia ...