Petter Brodin, Giorgio Casari, Liam Townsend, Cliona O’Farrelly et al.
Saraswati Kache, Mohammod Jobayer Chisti, Felicity Zvanyadza Gumbo, Ezekiel Mupere et al.
BACKGROUND: Fewer children than adults have been affected by the COVID-19 pandemic, and the clinical manifestations are distinct from those of adults. Some children particularly those with acute or chronic co-morbidities are likely to develop critical illness. Recently, a multisystem inflammatory sy...
Chenchen Wei, Ya Liu, Yapeng Liu, Kai Zhang et al.
BACKGROUND: To investigate the clinical characteristics and manifestations of older patients with coronavirus disease 2019 (COVID-19). METHODS: In this retrospective study, 566 patients with confirmed COVID-19 were enrolled and the clinical characteristics, laboratory findings, complications and out...
Abdullah Al Mamun, Suzia Aktar Suchi, Md. Abdul Aziz, Muhammad Zaeem et al.
Pyroptosis defines a new type of GSDMs-mediated programmed cell death, distinguishes from the classical concepts of apoptosis and necrosis-mediated cell death and is prescribed by cell swelling and membrane denaturation, leading to the extensive secretion of cellular components and low-grade inflamm...
Gazi Mahabubul Alam
Higher education (HE) serves to produce well trained and job-ready graduates. Despite this belief, whether HE produces certificates/qualifications or job-ready graduates—this debate remains unsettled. To date, the current COVID-19 pandemic which erupted in late 2019 continues to create much economic...
J. H. Connolly, W. M. Hutchinson, Ingrid V. Allen, J A Lyttle et al.
The clinical, virological and pathological findings in 5 patients with neurological complications associated with rubella virus infection are described. The neurological illnesses began four to ten days after the rubella illnesses. The patients were all males aged between 6 and 17 years and were dia...
Saiful Amin, Salma Aktar, Md. Mijanur Rahman, Mohammed Mehadi Hassan Chowdhury
NLRP3 inflammasome is a critical immune component that plays a crucial role in mounting innate immune responses. The deleterious effects of inflammasome activation have been correlated with the COVID-19 disease severity. In the presence of several underlying disorders, the immune components of our b...
Yuhan Qin, Chengchun Tang, Changle Ma, Gaoliang Yan
BACKGROUND: Coronary artery ectasia (CAE) is the aneurysmal dilatation of the coronary artery, recognized as a special clinical form of coronary stenosis besides atherosclerosis. Its exact pathophysiological mechanism remains unknown. Moreover, few studies have focused on the relationship between tr...
Mohit Kehar, Noelle H. Ebel, Vicky L. Ng, Jairo Eduardo Rivera Baquero et al.
OBJECTIVE: Increased mortality risk because of severe acute respiratory syndrome coronavirus-2 (SARS-CoV2) infection in adults with native liver disease (LD) and liver transplant (LT) is associated with advanced age and comorbid conditions. We aim to report outcomes for children with LD and LT enrol...
Sidharth Kumar Sethi, Abhyuday Rana, Harsha Adnani, Mignon McCulloch et al.
The initial report of the multisystem inflammatory syndrome in children (MIS-C) was from the UK in April 2020; since then, cases have been reported worldwide. Renal involvement has been seen commonly, ranging from 10% to 46%. Kidney involvement following severe acute respiratory syndrome coronavirus...
Dragan Prokić, Goran Ristić, Zoran Paunovic, Srdjan Pašić
We report on pediatric patient with clinical and laboratory evidence of pancreatitis at onset of atypical Kawasaki disease (KD). In KD pancreatic inflammation was described previously, but clinical pancreatitis was rarely reported and its true incidence is unknown.In febrile pediatric patients suspe...
Mohammad Mizanur Rahman, José O Alvarez, Dilip Mahalanabis, Mohammad A. Wahed et al.
Kiran Shafiq Khan, Irfan Ullah
The pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causing coronavirus disease (COVID), has spread promptly globally.1, 2 In adults, COVID-19 shows classic symptoms that range from severe interstitial pneumonia to hyperactivation of the inflammatory cascade.3 In children, ...
Shahana A Rahman
Objectives: To assess the different clinical aspects of JIA patients as well as the disease activity status during follow-up period. This study also compared its findings with the previous baseline study done in our country. Methodology: A prospective observational study carried out in the departmen...
Jan David, Ondřej Hradský, Petr Jabandžiev, Eva Klásková et al.
In Spring 2020, following temporary success during the first wave of the world-wide pandemic of the novel 2019 coronavirus disease (COVID-19) with very few positive cases, the Czech Republic (CZ) subsequently suffered from one of the highest incidences of individuals who tested positive for severe a...