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Field: Medicine

Amebiasis

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Rashidul Haque, Christopher D. Huston, Molly A. Hughes, Eric R. Houpt et al.

Journal: New England Journal of MedicineYear: 2003Citations: 829

Infection with Entamoeba histolytica can lead to amebic colitis and to complications including liver abscess. This review summarizes recent research on the pathogenesis and treatment of infection and the prospects for the development of a vaccine. A mucosal IgA response can produce partial, protecti...

Health SciencesMedicineInfectious Diseases
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Zoonotic Diseases: Etiology, Impact, and Control

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Md. Tanvir Rahman, Md. Abdus Sobur, Md. Saiful Islam, Samina Ievy et al.

Journal: MicroorganismsYear: 2020Citations: 826

Most humans are in contact with animals in a way or another. A zoonotic disease is a disease or infection that can be transmitted naturally from vertebrate animals to humans or from humans to vertebrate animals. More than 60% of human pathogens are zoonotic in origin. This includes a wide variety of...

Health SciencesMedicinePublic Health, Environmental and Occupational HealthOpen Access
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Role of Phenolic Compounds in Human Disease: Current Knowledge and Future Prospects

Verified

Md. Mominur Rahman, Md. Saidur Rahaman, Md. Rezaul Islam, Firoza Rahman et al.

Journal: MoleculesYear: 2021Citations: 797

Inflammation is a natural protective mechanism that occurs when the body's tissue homeostatic mechanisms are disrupted by biotic, physical, or chemical agents. The immune response generates pro-inflammatory mediators, but excessive output, such as chronic inflammation, contributes to many persistent...

Health SciencesMedicineBiochemistryOpen Access
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Global and regional burden of hospital admissions for severe acute lower respiratory infections in young children in 2010: a systematic analysis

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Harish Nair, Eric A. F. Simões, Igor Rudan, Bradford D. Gessner et al.

Journal: The LancetYear: 2013Citations: 795

Background The annual number of hospital admissions and in-hospital deaths due to severe acute lower respiratory infections (ALRI) in young children worldwide is unknown. We aimed to estimate the incidence of admissions and deaths for such infections in children younger than 5 years in 2010. Methods...

Health SciencesMedicineEpidemiologyOpen Access
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Effect of Citrus Flavonoids, Naringin and Naringenin, on Metabolic Syndrome and Their Mechanisms of Action

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Md Ashraful Alam, Nusrat Subhan, Mahbubur Rahman, Shaikh Jamal Uddin et al.

Journal: Advances in NutritionYear: 2014Citations: 778

Flavonoids are important natural compounds with diverse biologic activities. Citrus flavonoids constitute an important series of flavonoids. Naringin and its aglycone naringenin belong to this series of flavonoids and were found to display strong anti-inflammatory and antioxidant activities. Several...

Health SciencesMedicineBiochemistryOpen Access
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Recommendations for the classification of group A rotaviruses using all 11 genomic RNA segments

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Jelle Matthijnssens, Max Ciarlet, Mustafizur Rahman, Houssam Attoui et al.

Journal: Archives of VirologyYear: 2008Citations: 769

Recently, a classification system was proposed for rotaviruses in which all the 11 genomic RNA segments are used (Matthijnssens et al. in J Virol 82:3204-3219, 2008). Based on nucleotide identity cut-off percentages, different genotypes were defined for each genome segment. A nomenclature for the co...

Health SciencesMedicineInfectious DiseasesOpen Access
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Donepezil and Memantine for Moderate-to-Severe Alzheimer's Disease

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Robert Howard, Rupert McShane, James Lindesay, Craig Ritchie et al.

Journal: New England Journal of MedicineYear: 2012Citations: 763

BACKGROUND: Clinical trials have shown the benefits of cholinesterase inhibitors for the treatment of mild-to-moderate Alzheimer's disease. It is not known whether treatment benefits continue after the progression to moderate-to-severe disease. METHODS: We assigned 295 community-dwelling patients wh...

Health SciencesMedicinePsychiatry and Mental healthOpen Access
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Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific Association for the study of the liver (APASL)

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Shiv Kumar Sarin, Ashish Kumar, John Almeida, Yogesh Chawla et al.

Journal: Hepatology InternationalYear: 2008Citations: 762

The Asian Pacific Association for the Study of the Liver (APASL) set up a working party on acute-on-chronic liver failure (ACLF) in 2004, with a mandate to develop consensus guidelines on various aspects of ACLF relevant to disease patterns and clinical practice in the Asia-Pacific region. Experts p...

Health SciencesMedicineHepatologyOpen Access
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Diabetes mellitus, the fastest growing global public health concern: Early detection should be focused

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Md. Jamal Hossain, Md. Al‐Mamun, Md. Rabiul Islam

Journal: Health Science ReportsYear: 2024Citations: 745

Background and Aims: Diabetes is recognized as a significant factor in both mortality and morbidity worldwide, affecting various demographics regardless of geographic location, age group, or gender. This correspondence aims to express concern and draw the attention of leaders and policymakers worldw...

Health SciencesMedicineEndocrinology, Diabetes and MetabolismOpen Access
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Risk of Malignant Progression in Barrett's Esophagus Patients: Results from a Large Population-Based Study

Verified

Seema A. Bhat, Helen G. Coleman, Foad Yousef, B. T. Johnston et al.

Journal: JNCI Journal of the National Cancer InstituteYear: 2011Citations: 742

BACKGROUND: Barrett's esophagus (BE) is a premalignant lesion that predisposes to esophageal adenocarcinoma. However, the reported incidence of esophageal adenocarcinoma in patients with BE varies widely. We examined the risk of malignant progression in patients with BE using data from the Northern ...

Health SciencesMedicineSurgeryOpen Access
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Rising rural body-mass index is the main driver of the global obesity epidemic in adults

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Honor Bixby, James Bentham, Bin Zhou, Mariachiara Di Cesare et al.

Journal: NatureYear: 2019Citations: 741

Abstract Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities 1,2 . This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity 3–6 . Here we use 2...

Health SciencesMedicinePublic Health, Environmental and Occupational HealthOpen Access
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Improved health outcomes in patients with COPD during 1 yr's treatment with tiotropium

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Walter Vincken, J.A. van Noord, A.P.M. Greefhorst, Th.A. Bantje et al.

Journal: European Respiratory JournalYear: 2002Citations: 736

Tiotropium, a novel once-daily inhaled anticholinergic, has been shown to improve lung function over a 24-h period. In order to extend these findings, health-outcomes were evaluated over 1 yr in chronic obstructive pulmonary disease (COPD) patients. Spirometric results, peak expiratory flow rate (PE...

Health SciencesMedicinePulmonary and Respiratory MedicineOpen Access
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Development and validation of the Dundee Ready Education Environment Measure (DREEM)

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Sue Roff, Sean McAleer, Ronald M. Harden, Mona Faisal Al-Qahtani et al.

Journal: Medical TeacherYear: 1997Citations: 735

The General Medical Council has initiated major innovations in the undergraduate medical curriculum. These requirements are forcing a rapid rate of change in medical schools throughout the UK which parallels many developments in North America. There have also been several international and national ...

Health SciencesMedicinePublic Health, Environmental and Occupational Health
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Global and regional prevalence of multimorbidity in the adult population in community settings: a systematic review and meta-analysis

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Saifur Rahman Chowdhury, Dipak Chandra Das, Tachlima Chowdhury Sunna, Joseph Beyene et al.

Journal: EClinicalMedicineYear: 2023Citations: 728

Background: Knowing the prevalence of multimorbidity among adults across continents is a crucial piece of information for achieving Sustainable Development Goal 3.4, which calls for reducing premature death due to non-communicable diseases. A high prevalence of multimorbidity indicates high mortalit...

Health SciencesMedicineEpidemiologyOpen Access
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Causes of Death in U.S. Special Operations Forces in the Global War on Terrorism

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John B. Holcomb, Neil R. McMullin, Lisa Pearse, Jim Caruso et al.

Journal: Annals of SurgeryYear: 2007Citations: 687

In Brief Background: Effective combat trauma management strategies depend upon an understanding of the epidemiology of death on the battlefield. Methods: A panel of military medical experts reviewed photographs and autopsy and treatment records for all Special Operations Forces (SOF) who died betwee...

Health SciencesMedicineCritical Care and Intensive Care MedicineOpen Access
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